New shot aims to ease pain after arm surgery
NCT ID NCT07131657
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new injectable painkiller called Ropiclobet in 40 adults having arm, elbow, forearm, or hand surgery. The injection was given near the shoulder to numb the arm and control pain after surgery. Researchers measured how long pain relief lasted and checked for side effects over 30 days.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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40 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Dec 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female patients with age of ≥18 years and ≤ 65 years at the time of consent. * Ability and willingness to provide informed consent or consent from their legal representative and willingness to comply with all planned visits and study procedures. * American Society of Anesthesiologists (ASA) physical status class of I-III * BMI ≤ 30 kg/m2 * An ECG within normal values or clinically insignificant findings. * Patients undergoing upper extremity procedures suitable for SCB anesthesia, including arm, elbow, forearm, and hand surgeries. * Emergency and/or elective surgeries * Women of childbearing potential (WOCBP) must have a negative urine pregnancy testing at screening visit. Exclusion Criteria: * An inability to cooperate during the block placement. * Patients undergoing shoulder procedures. * History of allergy to active ingredients (including their derivatives) of the study medication. * History of allergy to analgesics (e.g. acetaminophen, non-steroidal anti-inflammatory medications, oral opioid analgesics) * History of shoulder or clavicular surgery. * Known bronchopulmonary or phrenic pathology compromising respiratory function. * Existing chronic pain disorders or history of use of ≥ 30mg oxycodone or equivalent per day * Pre-existing neurological deficits or peripheral neuropathy involving the operative upper extremity * Infection at the puncture site for the block. * History of coagulopathy disorders and/or bleeding diathesis. * Pregnant or breastfeeding. * History of any documented medical condition considered to be clinically significant and could potentially affect patient safety or study outcome, in the opinion of the investigator: uncontrolled diabetes, uncontrolled hypertension, cardiovascular diseases, acute or chronic kidney diseases, liver diseases, psychiatric disorders, malignancy, systemic infection. * Any clinically significant abnormal findings in physical examination, vital signs, hematology, clinical chemistry, or urinalysis during screening which, in the opinion of the investigator, may put the patient at risk because of his/her participation in the study, or might influence the results of the study, or the patient's ability to complete the entire duration of the study. * Participation in a clinical trial involving current or another investigational product in the previous 3 months. * Currently taking long-term systemic steroids (excluding inhaled medication for asthma treatment)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul Medeniyet University, Göztepe Prof. Dr. Süleyman Yalçın City Hospital
Istanbul, 34722, Turkey (Türkiye)
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