Brain scans and genetics may predict anorexia relapse
NCT ID NCT04560517
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study follows 125 women with anorexia nervosa during and after intensive inpatient treatment to understand why relapse happens. Researchers will use brain imaging, genetic tests, and behavioral tasks to look for patterns. The goal is to find factors that help predict who stays well and who relapses, which could lead to better long-term care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal key factors that predict long-term recovery from anorexia nervosa, helping doctors personalize treatment to prevent relapse.
- What could go wrong
- This is an observational study, not a treatment trial. It may not identify clear causes of relapse, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 275 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2021
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients : all female patients integrating inpatient treatment program for Anorexia Nervosa at the Clinique des Maladies Mentales et de l'Encéphale in Paris, France Control group : Female aged from 18 to 65 years old without any psychiatric disorder
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * DMS 5 criteria for Anorexia Nervosa * BMI \< 18.5 kg/m² * Being able to consent * fluent in French * Being affiliated to a social security scheme or being the beneficiary of such a scheme. * Having signed the informed consent Exclusion Criteria: * Deprived of liberty subject (judicial or administrative decision) * Refusal to participate * Presenting an unstabilized serious physical illness or psychiatric disorder compromising the follow up according investigator evaluation * Contraindication for IRMf * Pregnant or breast-feeding women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Hospitalier St Anne
RECRUITINGParis, 75014, France
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Other studies related to the condition(s) this trial covers.
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- Could the gut microbiome hold clues to eating disorder recovery?
- Can a parent support group help teens with both autism and anorexia?
- Lab-Grown brain cells could unlock Anorexia's secrets
- Can science unlock the secrets of the naturally lean?