Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Lab-Grown brain cells could unlock Anorexia's secrets

NCT ID NCT06259500

Knowledge-focused Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study uses stem cell technology to create brain cells from people with anorexia nervosa and compare them to cells from healthy individuals. The goal is to understand how specific brain cells, called hypothalamic neurons and microglia, function differently in anorexia. By profiling these cells, researchers hope to identify new molecules that could be explored as drug targets for this condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Patient-derived induced pluripotent stem cells (iPSCs) and peripheral blood mononuclear cell (PBMC) derived microglia
What this could lead to
If successful, this research could identify specific molecules involved in anorexia nervosa that might serve as targets for future drug development.
What could go wrong
This is an early-stage laboratory study with a small number of participants. Findings from cell models may not fully reflect what happens in the human brain, and any potential treatments would be far off.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Aug 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients recruited from specialised care unit Controls from community

Ages

18 to 45 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria anorexia nervosa: * female * 18-45 years of age * AN restrictive diagnosis as main diagnosis * more than 5 years duration Exclusion Criteria anorexia nervosa: \- Inclusion Criteria healthy control: * female * 18-45 years of age * BMI 18,5 - 25 Exclusion Criteria healthy control: * own or family member with eating disorder diagnosis * own or family member with autism diagnosis

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anorexia nervosa are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

anorexia nervosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa

Contacts and locations

Locations

  • Karolinska Institutet

    Stockholm, 17176, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.