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Can community navigation cut cancer delays? botswana trial aims to find out

NCT ID NCT04141449

Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called Potlako+ that combines community education, support for healthcare providers, and patient navigation to help people with cancer symptoms get diagnosed and treated faster. About 874 participants in Botswana will be split into two groups: one receiving the full Potlako+ program, the other getting standard care. The goal is to see if the program reduces the time from noticing symptoms to starting treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Potlako+ intervention (community education, clinical provider support, patient navigation)
What this could lead to
If successful, this could show that a coordinated community-based program helps catch cancer earlier and get people into treatment faster.
What could go wrong
This is a Phase 2 trial in specific communities in Botswana, so results may not apply elsewhere. The intervention is complex and may not work as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

874 people

The number who actually took part.

Started

Nov 2020

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1. Community members 1. Inclusion Criteria: * Botswana citizen * Age 30 years or older * engaged in longitudinal care for chronic health problem * resident of study community 2. Exclusion Criteria: * Involuntary incarceration * Educational messaging could interfere with clinical management or increase distress in the opinion or clinic or research staff 2. Cancer suspects 1. Inclusion Criteria: * Botswana citizen * Age 30 years or older * resident of study community * Recorded as a cancer suspect by clinic staff 2. Exclusion Criteria * Involuntary incarceration * Unable or unwilling to provide confirmation of informed consent * Already engaged in oncology care

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Conditions

The condition(s) this trial relates to.

AIDS anal carcinoma anus neoplasm breast cancer breast neoplasm cervical cancer head and neck squamous cell carcinoma HIV infectious disease neoplasm Squamous Cell Carcinoma of Head and Neck Uterine Cervical Neoplasms vulva cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anal cancer Breast cancer Cancer suspect Cervical cancer HIV HNSCC Neoplasms Vulvar cancer

Contacts and locations

Locations

  • Botswana Harvard AIDS Institute

    Gaborone, Botswana

More trials for these conditions

Other studies related to the condition(s) this trial covers.