5,000 patients help uncover how common Post-Surgery brain fog really is
NCT ID NCT02832193
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study reviews data from 5,000 adults aged 18-100 who had surgery lasting at least an hour. The goal is to find out how often people experience brain fog (called postoperative cognitive dysfunction or POCD) after surgery. No new treatments are being tested—researchers are just looking at past information to better understand the problem.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2009
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Male and female patients undergoing surgery, screened at the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Study Group Inclusion Criteria: * Age 18 -100 years * Male or female patients undergoing elective surgery expected to last at least 60 min, screened at the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany * Written informed consent to participate after having been properly instructed Exclusion Criteria: * Lacking willingness to take part in the study, or to have relevant study data collected, saved and analyzed for the purpose of the study * Accommodation in an institution due to an official or judicial order * Insufficient knowledge of German language * Members of the hospital staff * Homelessness or other conditions that disable reachability for postoperative assessment by post or telephone * Illiteracy * Patients who had a history of neurologic deficits (e.g. stroke, history of seizures, etc.) * Hearing impairment that severely affects the neuropsychological testing. * Visual impairment that severely affects the neuropsychological testing. * Participation in other prospective clinical interventional trials Control Group Inclusion Criteria: * Age 18 - 100 years * Male or female patients (ASA Status I, II+III) * No planned surgery during the next 3 months * No surgery during the past 6 months before study inclusion * Written informed consent to participate after having been properly instructed Exclusion Criteria: * Insufficient knowledge of German language Lacking willingness to take part in the study, or to have relevant study data collected, saved and analyzed for the purpose of the study * Neuropsychiatric conditions that severely affect the neuropsychological testing * Hearing impairment that severely affects the neuropsychological testing * Visual impairment that severely affects the neuropsychological testing
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Anesthesiology and Operative Intensive Care Medicine Berlin (CCM, CVK), Charité - Universitätsmedizin Berlin
RECRUITINGBerlin, 13353, Germany
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Irmgard Landgraf
NOT_YET_RECRUITINGBerlin, 12163, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a natural supplement shield the aging brain from Surgery's mental fog?
- Could a new anesthetic keep your mind sharper after a procedure?
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- Keto diet before bypass surgery may shield seniors from brain fog
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