Can exercise change how aging athletes feel pain?
NCT ID NCT07502742
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how former athletes, current master's athletes, and nonathletes (ages 35-65) experience pain and respond to moderate exercise. Participants will do strength and aerobic exercises while their pain tolerance and sensitivity are measured. The goal is to understand if past athletic training affects pain perception and how different exercises influence it.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- moderate-intensity strength and aerobic exercise
- What this could lead to
- If successful, this study could help tailor exercise-based pain management strategies for aging athletes and nonathletes.
- What could go wrong
- This is an early-stage observational trial with a small sample size (90 participants). Results may not apply to all populations or pain types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (General): * Age: 35 years through 65 years * Current master's athlete, former competitive athletes, or non-athlete control (see details below) * Ability to participate in exercise and exercise testing based on the Physical Activity Readiness Questionnaire (PAR-Q+) Exclusion Criteria (General): * Currently pregnant or planning to become pregnant during the study * Currently taking heart rate lowering medications (e.g., betablockers) that would impact exercise testing * Contraindications to ice such as Raynaud's, cryoglobulinemia, cold urticaria, and/or impaired circulation or sensation * Fibromyalgia and/or chronic regional pain syndrome (CRPS) * Myocardial infarction or pulmonary embolism in the last 12 months, active cancer, a pacemaker, or any additional condition or disease that would preclude the individual from being able to perform the tests safely Participants will be enrolled into one of the following three mutually exclusive groups according to the following criteria: 1. Former Competitive Athlete: Prior participation in competitive sports at the Tier 3 level or above as per McKay et al. (2022): i.e., "national-level representatives who are performing structured and/or periodized training and are developing proficiency in skills required to perform their sport at the highest level; this tier includes individuals participating in Provincial/State or Academy Programs" or higher participation in sport; Not currently participating in any recreational or competitive sports over the last 5 years (Tier 2 or above) 2. Master's Athlete: Currently (within the past year) participating in sports at the Tier 2 level or above (i.e., committed to sports-specific training at least 3 times per week with the intent to compete)(McKay et al., 2022) 3. Nonathlete Control: No prior participation in sport at the Tier 3 (Highly Trained/National) Level or above and not currently participating in any competitive sports (i.e., Tier 2 or above) (McKay et al., 2022) for at least 5 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Marquette University
RECRUITINGMilwaukee, Wisconsin, 53233, United States
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