Could a simple ultrasound replace liver biopsies for this rare disease?
NCT ID NCT07492862
First seen Mar 29, 2026 · Last updated Jun 22, 2026 · Updated 17 times
Summary
This study explores whether a special ultrasound technique, called dynamic contrast-enhanced ultrasound (DCE-US), can diagnose porto-sinusoidal vascular disorder (PSVD) without needing a liver biopsy. Researchers will compare ultrasound images from 100 people with PSVD or cirrhosis to see if blood flow patterns differ. If it works, this painless test could make diagnosis easier and faster.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, RM, 00168, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
contrast-enhanced ultrasound with VueBox software
What this could lead to
If successful, this could provide a noninvasive way to diagnose PSVD, avoiding the need for a liver biopsy.
What could go wrong
This is an early exploratory study with only 100 participants, so results may not be conclusive or widely applicable. The technique may not reliably distinguish PSVD from cirrhosis.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.