PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Clinical trials for PORTAL HYPERTENSION RELATED TO CIRRHOSIS explained in plain language.
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Can amino acid supplements help reverse muscle wasting in liver disease patients?
Disease control Recruiting nowThis study looks at whether adding branched-chain amino acid (BCAA) supplements to a standard liver procedure (TIPS) can help reverse muscle loss (sarcopenia) in people with cirrhosis and high blood pressure in the liver. About 164 patients will be randomly assigned to receive ei…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated Jun 23, 2026 22:17 UTC
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New combo treatment aims to ease liver pressure and boost weight loss
Disease control Recruiting nowThis study tests whether a two-step procedure—first a TIPS shunt to lower liver pressure, then sleeve gastrectomy surgery for weight loss—can improve quality of life and help people with cirrhosis and severe obesity lose more weight than standard medical care alone. About 70 adul…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: PHASE4 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 22, 2026 12:06 UTC
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New stent aims to ease Life-Threatening complications of cirrhosis
Disease control Recruiting nowThis study is testing a special stent (a small mesh tube) called LIVERTY TIPS to help people with cirrhosis who have high blood pressure in the liver. The stent is placed to create a new path for blood flow, which can reduce dangerous complications like internal bleeding or fluid…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 22, 2026 12:04 UTC
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Could a common heart drug prevent deadly bleeding in liver disease?
Disease control Recruiting nowThis study tests whether carvedilol, a beta-blocker, can reduce high blood pressure in the liver's portal vein in people with cirrhosis. High pressure can lead to life-threatening bleeding. Thirty adults with cirrhosis and signs of portal hypertension will take carvedilol for one…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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Spleen scan could spare liver patients risky needle test
Diagnosis Recruiting nowThis study is testing whether a non-invasive ultrasound of the spleen can accurately detect dangerous vein swelling and high blood pressure in the liver. Researchers will enroll 450 adults with advanced chronic liver disease. If successful, this simple scan could replace the curr…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 16, 2026 12:50 UTC
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New scope technique may predict liver pill success
Knowledge-focused Recruiting nowThis study tests if a special ultrasound done through a scope (endoscopic ultrasound) can measure whether a common blood pressure pill (carvedilol) is working in people with liver scarring (cirrhosis). 24 adults will get the scope test before and after 3 months of treatment. The …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Can a quicker MRI beat ultrasound for spotting liver cancer?
Knowledge-focused Recruiting nowThis study looks at 600 adults with liver cirrhosis to see if a shorter MRI scan works better than ultrasound for finding early liver cancer. Researchers will also track body composition and other health changes over time. The goal is to improve how doctors monitor and predict li…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Mattias Ekstedt • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Liver clot study seeks to predict recovery in 1,500 patients
Knowledge-focused Recruiting nowThis study looks at factors that help blood clots in the main liver vein dissolve in people with liver scarring (cirrhosis) and enlarged stomach veins. Researchers will follow 1,500 patients over time to see what influences clot recovery. The goal is to help doctors and patients …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:10 UTC
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Tiny plastics, big trouble: new study links microplastics to liver damage
Knowledge-focused Recruiting nowThis study looks at whether tiny plastic particles (microplastics and nanoplastics) build up in the liver and worsen cirrhosis and heart problems. Researchers will compare liver tissue from 30 people with cirrhosis to people without liver disease. The goal is to understand how pl…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated Jun 02, 2026 11:58 UTC