PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Clinical trials for PORTAL HYPERTENSION RELATED TO CIRRHOSIS explained in plain language.
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New combo therapy aims to tackle liver disease and obesity together
Disease control Recruiting nowThis study tests whether a two-step treatment—first a procedure to lower liver pressure (TIPS), then weight-loss surgery (sleeve gastrectomy)—improves quality of life and weight loss more than standard medical care alone. It includes 70 adults with cirrhosis, severe obesity, and …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: PHASE4 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 26, 2026 05:02 UTC
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Protein boost may help liver patients regain muscle after key procedure
Disease control Recruiting nowThis study looks at 164 adults with cirrhosis (scarred liver) who also have severe muscle loss (sarcopenia) and need a procedure called TIPS to treat complications like bleeding. Half will get TIPS alone, and half will get TIPS plus branched-chain amino acid (BCAA) supplements. T…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New stent could help control liver cirrhosis complications
Disease control Recruiting nowThis study is testing a device called the LIVERTY TIPS stent graft in 166 people with cirrhosis and related high blood pressure in the liver. The goal is to see if the stent stays open and helps control problems like internal bleeding or fluid buildup in the belly. Participants w…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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Spleen scan may spare liver patients from painful needle tests
Diagnosis Recruiting nowThis study looks at whether a non-invasive ultrasound technique that measures spleen stiffness can accurately detect dangerous liver blood pressure and high-risk varicose veins in the esophagus. Researchers will enroll 450 adults with advanced chronic liver disease. Participants …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated May 22, 2026 14:04 UTC
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Can a common heart drug prevent deadly bleeding in liver disease?
Prevention Recruiting nowThis study tests whether carvedilol, a drug usually used for heart conditions, can lower high blood pressure in the liver's main vein to prevent dangerous bleeding in people with cirrhosis. About 30 adults with cirrhosis and signs of high liver pressure will take carvedilol for o…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Prevention
Last updated May 22, 2026 13:52 UTC
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Tiny plastics, big trouble? new study links microplastics to liver damage
Knowledge-focused Recruiting nowThis study looks at whether tiny plastic particles (microplastics and nanoplastics) build up in the liver and worsen cirrhosis and heart problems. Researchers will compare tissue samples from 30 people with cirrhosis to those without liver disease. The goal is to understand how p…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated May 26, 2026 05:02 UTC
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Can a quicker MRI beat ultrasound for spotting liver cancer?
Knowledge-focused Recruiting nowThis study looks at 600 adults with liver cirrhosis to see how well ultrasound and a shorter MRI scan find early liver cancer. Researchers will also track body composition and other health changes over time. The goal is to find better ways to monitor patients and predict who is a…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Mattias Ekstedt • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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New study seeks clues to clearing dangerous liver clots in cirrhosis patients
Knowledge-focused Recruiting nowThis study looks at people with cirrhosis (scarred liver) who also have a blood clot in the main liver vein and enlarged veins in the stomach. Researchers want to find out what helps these clots dissolve over time. The goal is to help doctors and patients better understand the di…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC