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Could a urine test replace repeated scopes for kids with eosinophilic esophagitis?

NCT ID NCT06387030

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 29 times

Summary

This study is testing whether simple, noninvasive tests (like urine, blood, or mouth swabs) can track disease activity in children with eosinophilic esophagitis, a chronic allergic condition that inflames the esophagus. Currently, kids need repeated endoscopies under anesthesia to check if treatments are working. The researchers will measure a protein called EDN and study gut bacteria in 60 children to see if these markers can reliably tell if the disease is active or in remission. If successful, this could lead to a less invasive, more child-friendly way to manage the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nutrition et gastro-entérologie pédiatrique-Trousseau Hospital

    RECRUITING

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

allergic disease eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.