300 kids with EoE enrolled in landmark database study
NCT ID NCT05176249
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study gathers information from 300 children with eosinophilic esophagitis (EoE), a chronic allergic condition that inflames the esophagus. Researchers aim to better understand what causes EoE, how it relates to other allergies, and which treatments work best. No new treatments are given; instead, the team analyzes medical records and follows patients over time to improve future care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2011
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study population is determined through general GI and EOE specific clinics. Patients who are undergoing pre-diagnostic endoscopies to change of treatments are enrolled into this study.
- Ages
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1 month to 21 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: -Patients with an established diagnosis of EoE, based on endoscopy with biopsies with ≥15 eosinophils per hpf in esophageal biopsies after symptoms of esophageal dysfunction persist despite at least 6-8 weeks of appropriate acid suppression therapy. OR -Patients who are suspected of having EoE (presenting with symptoms of esophageal dysfunction non-responsive to appropriate proton pump inhibitor therapy for 6-8 weeks). • Note: Patients suspected of having EoE but not diagnosed with EoE by endoscopy with biopsies will serve as control patients Exclusion Criteria: * Patients who do not consent to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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