Could a common diabetes pill boost arthritis remission?
NCT ID NCT04196868
First seen Feb 03, 2026 · Last updated Jun 17, 2026 · Updated 21 times
Summary
This study tests whether adding metformin, a diabetes drug, to standard methotrexate therapy helps more people with rheumatoid arthritis achieve disease control. About 128 adults with active RA who have not recently taken methotrexate will receive either methotrexate plus metformin or methotrexate plus a placebo. The goal is to see if the combination reduces joint inflammation and disease activity better than methotrexate alone.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CH de Cahors - service de rhumatologie
Cahors, France
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CH de Libourne - service de rhumatologie
Libourne, France
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CH de Pau - service de rhumatologie
Pau, France
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CH de la Côte Basque - service de rhumatologie
Bayonne, France
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CH du Mans - service de rhumatologie
Le Mans, France
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CHD de Vendée - service de rhumatologie
La Roche-sur-Yon, France
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CHR Orléans la Source - service de rhumatologie
Orléans, France
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CHU de Bordeaux - service de rhumatologie
Bordeaux, France
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CHU de Brest - service de rhumatologie
Brest, France
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CHU de Montpellier - service de rhumatologie
Montpellier, France
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CHU de Toulouse - service de rhumatolgie
Toulouse, France
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Clinique de l'Infirmerie protestante de Lyon - service de rhumatologie
Caluire-et-Cuire, France
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.