ARTHRITIS, RHEUMATOID

This early-stage study tests whether an oral probiotic called R-2487 is safe for people with rheumatoid arthritis. About 73 adults with active RA will take the probiotic by mouth, and doctors will monitor side effects and measure joint swelling and inflammation. The goal is to se…

This study tests a personalized approach to slowly reduce the dose of a biologic drug (adalimumab) for adults with stable rheumatoid arthritis. The goal is to find the best blood level of the drug before each dose reduction to lower the chance of a flare-up. 180 participants in r…

This study is monitoring the safety and effectiveness of the drug Jyseleca (filgotinib) in Korean patients with rheumatoid arthritis or ulcerative colitis. About 2,040 participants will be followed for 24 weeks to track side effects and disease activity. The goal is to confirm th…

This study tests a new medicine called tulisokibart for people with rheumatoid arthritis who are already taking methotrexate. The goal is to see if tulisokibart can reduce joint pain and swelling better than a placebo. About 182 adults with active arthritis will receive different…

This study tests fucoidan, a substance from brown seaweed, in 40 adults with active rheumatoid arthritis who haven't improved with standard drugs. The goal is to see if fucoidan can reduce joint pain and swelling over 12 weeks. This is an early-phase trial to gather initial evide…

This study is testing a new, non-invasive imaging method called photoacoustic tomography (PAT) to see if it can help diagnose chronic rheumatoid arthritis. Researchers will scan the joints of 113 adults who have had arthritis for over 2 years, as well as healthy volunteers. The g…

This study tests the safety of a small device placed in the belly to stimulate the vagus nerve for people with moderate to severe rheumatoid arthritis that hasn't improved with medication. Only 5 adults aged 18-75 will join, and they will be monitored for 5 years after the device…

This study aims to better understand why people with inflammatory arthritis (like rheumatoid or psoriatic arthritis) experience chronic pain. Researchers will follow 350 patients starting new medications to identify different pain types and risk factors. The goal is to pave the w…

This study looks at how natural cannabis compounds (like CBD and THC) affect immune cells from 100 people with chronic inflammatory diseases such as rheumatoid arthritis, lupus, and inflammatory bowel disease. Researchers will take a blood sample and expose the cells to different…