ARTHRITIS, RHEUMATOID

This early-stage study is testing whether an oral probiotic called R-2487 is safe for people with rheumatoid arthritis. Researchers will also check if it reduces joint swelling and inflammation. The trial involves 73 adults with active RA who will take the probiotic and be monito…

This study is monitoring the safety and effectiveness of the drug Jyseleca (filgotinib) in Korean patients with rheumatoid arthritis or ulcerative colitis. Researchers will track side effects and disease activity over 24 weeks. About 2,040 participants are being observed during r…

This study tests whether fucoidan, a substance from brown seaweed, can help adults with active rheumatoid arthritis who haven't improved enough on standard medications. The trial will enroll 40 people and follow them for 12 weeks to see if joint pain and swelling improve. Fucoida…

This study tests a personalized approach to slowly reduce the dose of the biologic drug adalimumab in people with rheumatoid arthritis who are in remission. The goal is to find the best blood level of the drug before each dose reduction to lower the risk of disease flares. 180 ad…

This early study tests whether a device that electrically stimulates the abdominal vagus nerve is safe for people with moderate to severe rheumatoid arthritis that hasn't improved with medication. Five participants will have the device implanted via keyhole surgery and receive da…

This study is testing whether a new laser-based imaging technique, called photoacoustic tomography (PAT), can help diagnose rheumatoid arthritis. Researchers will scan the finger joints of 113 adults—some with arthritis and some healthy—and compare PAT with MRI and ultrasound. Th…

This study aims to better understand why people with inflammatory arthritis experience chronic pain. Researchers will look at how the brain processes pain and how it affects daily life. 350 adults starting or switching arthritis medications will be followed over time. The goal is…

This study looks at how natural cannabis compounds (phytocannabinoids) affect immune cells from 100 people with chronic inflammatory diseases like rheumatoid arthritis, lupus, and Crohn's disease. Researchers will take a blood sample and expose the cells to different cannabis ext…