ARTHRITIS, RHEUMATOID

This study tests a new medicine called tulisokibart for people with rheumatoid arthritis who are already taking methotrexate. The goal is to see if tulisokibart can reduce joint pain and swelling better than a placebo. About 182 adults with active arthritis will receive different…

This study is for adults with rheumatoid arthritis whose disease is well-controlled (in remission) for at least 6 months while taking the biologic drug adalimumab. Researchers want to see if a personalized plan to gradually lower the drug dose can prevent disease flare-ups. The g…

This study tests whether fucoidan, a substance from brown seaweed, can help people with active rheumatoid arthritis who haven't gotten better with usual medications. The trial will enroll 40 adults and follow them for 12 weeks to see if joint pain and swelling improve. Fucoidan w…

This early-stage study tests whether an oral probiotic called R-2487 is safe for people with rheumatoid arthritis. About 73 adults with active arthritis will take the probiotic by mouth. Researchers will monitor side effects and check if the treatment reduces joint swelling and i…

This study is checking the safety and effectiveness of the drug Jyseleca (filgotinib) in Korean patients with rheumatoid arthritis or ulcerative colitis. About 2040 people will take the drug as prescribed by their doctor, and researchers will track side effects and how well the d…

This study tests a new imaging method called photoacoustic tomography (PAT) to see if it can help diagnose rheumatoid arthritis. Researchers will scan the joints of people with arthritis and healthy volunteers every two weeks for up to 10 weeks. The goal is to find out if PAT can…

This study tests whether a device that electrically stimulates the abdominal vagus nerve is safe for people with moderate to severe rheumatoid arthritis that hasn't responded to standard medications. Five adults will have the device implanted via keyhole surgery and receive stimu…

This study aims to understand why people with inflammatory arthritis (like rheumatoid or psoriatic arthritis) feel chronic pain. Researchers will follow 350 patients starting new medications to identify different pain types and risk factors. The goal is to pave the way for more p…

This study looks at how natural cannabis compounds (phytocannabinoids) affect immune cells from 100 people with chronic inflammatory diseases like rheumatoid arthritis, lupus, and inflammatory bowel disease. Researchers will take blood samples and expose the cells to different ca…