Could a probiotic tame rheumatoid arthritis? early trial begins
NCT ID NCT05961592
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study is testing whether an oral probiotic called R-2487 is safe for people with rheumatoid arthritis. Researchers will also check if it reduces joint swelling and inflammation. The trial involves 73 adults with active RA who will take the probiotic and be monitored for side effects and changes in their disease activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probiotic (R-2487)
What this could lead to
If it works, this could point toward a new, gentle treatment option for rheumatoid arthritis that uses a probiotic instead of strong drugs.
What could go wrong
This is a very early Phase 1 trial with only 73 people, focused on safety. It is too soon to know if the probiotic will actually help arthritis symptoms.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP Medical Research
RECRUITINGMiami, Florida, 33165, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Altoona Center for Research
RECRUITINGDuncansville, Pennsylvania, 16635, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Edward Jenner Research
RECRUITINGPlantation, Florida, 33317, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Prolato Clinical Research Center
RECRUITINGHouston, Texas, 77054, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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St.Jude Clinical Research
RECRUITINGDoral, Florida, 33172, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, San Diego
RECRUITINGSan Diego, California, 92037, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••