Brain scans may predict who gets long-term pain from arthritis

NCT ID NCT05038553

Ongoing Knowledge-focused Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why some people with early rheumatoid arthritis develop long-lasting chronic pain while others do not. Researchers will use pain sensitivity tests and brain scans to find clues. The goal is to better understand the transition from acute to chronic pain, which could one day lead to better prevention or treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could identify early warning signs and targets to prevent chronic pain in people with rheumatoid arthritis.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to any direct medical changes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHRITIS, RHEUMATOID PAIN

Contacts and locations

Locations

Hospital for Special Surgery

New York, New York, 10021, United States
Johns Hopkins University

Baltimore, Maryland, 21224, United States
Northwestern University

Chicago, Illinois, 60611, United States
University of Colorado

Denver, Colorado, 80045, United States
University of Michigan

Ann Arbor, Michigan, 48019, United States

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