Brain scans may predict who gets long-term pain from arthritis

NCT ID NCT05038553

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why some people with early rheumatoid arthritis develop long-lasting chronic pain while others do not. Researchers will use pain sensitivity tests and brain scans to find clues. The goal is to better understand the transition from acute to chronic pain, which could one day lead to better prevention or treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could identify early warning signs and targets to prevent chronic pain in people with rheumatoid arthritis.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to any direct medical changes, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • University of Colorado

    Denver, Colorado, 80045, United States

  • University of Michigan

    Ann Arbor, Michigan, 48019, United States