ARTHRITIS, RHEUMATOID

This study compares two types of plastic used in total knee replacements: one with vitamin E and one without. About 605 adults with knee arthritis or similar conditions will be followed for years to see which material lasts longer and leads to better knee function. The goal is to…

This study follows 73 people aged 18-80 who received a specific shoulder replacement system for severe pain or disability from arthritis, injury, or bone death. Researchers will check how well the implant works and how long it lasts over 10 years using X-rays, shoulder function s…

This study was designed to see if a team-based program—including nurse education, home symptom tracking, and closer doctor-patient collaboration—could help more Hispanic adults with rheumatoid arthritis achieve remission. The study planned to enroll about 0 participants but was w…

This study follows 200 adults with ankle arthritis (rheumatoid, post-traumatic, or degenerative) who received the INFINITY ankle replacement. Researchers will check how long the implant lasts and monitor for problems like loosening or cysts over 10 years. The goal is to see if th…

This study tests whether adding metformin, a common diabetes drug, to standard methotrexate therapy helps more people with rheumatoid arthritis reach remission. About 128 adults with active RA who have not recently taken methotrexate will receive either methotrexate plus metformi…

This study follows 500 people who have received the INFINITY Total Ankle System to replace a damaged ankle joint due to arthritis or injury. Researchers will track how long the implant lasts and how it affects patients' pain, movement, and quality of life over up to 10 years. The…

This study looks at finger joints from people with rheumatoid arthritis who need joint replacement surgery. Researchers use advanced scans and tissue samples to see how bone damage happens. The goal is to learn more about the tiny blood vessels and pores in the bone that may be l…