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Gut bacteria may hold clues to stroke recovery

NCT ID NCT03934021

Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 120 people who had an acute ischemic stroke to see if the types of bacteria in their gut were linked to how well they recovered. Researchers analyzed stool samples and brain scans, and tracked disability over 6 months. The goal was to understand the role of gut microbes in stroke outcomes, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify gut bacteria patterns that influence stroke recovery, pointing toward future treatments.
What could go wrong
This is an observational study, not a treatment trial. It only looks for links between gut bacteria and stroke outcomes, so it won't directly improve patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

120 people

The number who actually took part.

Started

Jul 2018

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Consecutive patients diagnosed with acute ischaemic stroke during hospitalization in PWH will be recruited. Eligibility will be determined through a checklist of inclusion and exclusion criteria. Control group will be recruited from medical out patient clinic

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosed as acute ischaemic stroke 2. Aged 18 or above Chinese 3. Radiological evidence of acute ischaemic stroke by Computed tomography (CT) or magnetic resonance imaging (MRI) brain. Exclusion Criteria: 1. Patient with symptoms and signs suggestive of alternative diagnoses, 2. Evidence of intracerebral haemorrhage, 3. Absence of DWI evidence of acute ischaemic infarct, 4. Pregnancy, 5. Evidence of gastrointestinal infection/ inflammation/ obstruction 6. History of partial or total resection of small or large bowel, as well as gut re-anastomosis, 7. Use of antibiotics within 2 weeks prior to symptoms onset, 8. Gastrointestinal malignancy 9. Any hospitalization within 3 months before recruitment 10. Institutionalized patients

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Conditions

The condition(s) this trial relates to.

cerebral atherosclerosis intracranial arteriosclerosis ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atherosclerosis cerebral Microbiome Stroke Stroke, acute Stroke, ischemic

Contacts and locations

Locations

  • Chinese University of Hong Kong

    Hong Kong, Hong Kong

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