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Grape extract gummies vs capsules: which delivers more health-boosting flavanols?

NCT ID NCT06665958

Knowledge-focused Sponsor: University of Ulster Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study compares how well flavanols from grape seed extract are absorbed by the body when taken as a capsule or a gummy. Twenty-five healthy men aged 18–40 will each try both forms in a random order. The goal is to see which form leads to higher levels of flavanols in the blood, which could guide the development of better supplements and functional foods.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
grape seed extract (polyphenols)
What this could lead to
If successful, this could help develop better dietary supplements or functional foods that deliver more effective polyphenol health benefits.
What could go wrong
This is a small, early-stage study in healthy young men, so results may not apply to the general population or translate into real health effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Oct 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males * Aged 18-40 years at recruitment * BMI ≥ 20 and \< 30kg/m2 * Considered healthy based on their medical history and physical examination. * Subjects capable of and willing to comply with the protocol and to give their written informed consent. Exclusion Criteria: * Existing chronic disease including any; cardiovascular, neurological, gastric/intestinal, hepatic/pancreatic, renal or hematological diseases, obstructive cardiomyopathy, myocardial infarction, intracranial hypertension, diabetes mellitus (type I or II), chronic kidney disease, clinically significant arrhythmia, metabolic anomaly, ischaemia heart disease. * Uncontrolled Hypertension (\>160/100 mm Hg) or hypotension (\<100/60mm Hg) * Current use of any medication or narcotics within 2 weeks prior to study entry. * Currently on a clinically prescribed diet regimen. * Self-reported alcohol intake of \>10 units/ week * Have taken antibiotic therapy within the last 3 months * Following any specific diet (vegetarian, vegan, etc.) * Consumption of dietary supplement(s) currently or within 4 weeks prior to study entry (i.e. botanicals, vitamins, minerals, amino acids). * Weight change \> 10% of total body weight within the 6 months before entry to study. * Any intolerance or allergy documented or suspected to one of the components of the study products. * Having a psychological or linguistic inability to sign the informed consent; Under legal protection (guardianship, wardship) or deprived from his rights following administrative or judicial decision; * Subject participating in another biomedical study or participation in another study within the 3 months before entry into this study.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy nutrition

Contacts and locations

Locations

  • Ulster University,Human Intervention Studies UnitColeraine, Co. Londonderry BT521SA

    Coleraine, Co. Londonderry, BT52 1SA, United Kingdom

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