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Fish oil and exercise: a One-Two punch against obesity inflammation?

NCT ID NCT05295719

Disease control Sponsor: Texas Tech University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether taking fish oil and doing high-intensity interval training (HIIT) could lower inflammation in people who are overweight or obese. Researchers measured changes in blood markers of inflammation and metabolism over 10 weeks. The goal was to see if the combination works better than either alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Omega-3 fish oil (AlaskOmega) and high-intensity interval training (HIIT)
What this could lead to
If it works, this could point toward a simple way to lower inflammation and improve metabolic health in people with obesity.
What could go wrong
This is a small, early-stage study with only 129 participants. The results may not apply to everyone, and the effects might be modest or short-lived.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

129 people

The number who actually took part.

Started

Sep 2022

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-65 years old * Overweight/ Obese (BMI ≥ 25 to ≤ 40 kg/m2) * Elevated Triglycerides (\>150 mg/dL) * Prediabetes (fasting blood glucose 100 to 125 mg/dl) Exclusion Criteria: * Diagnosed with Diabetes or liver disease. * Taking BP or diabetes medications. * Received antibiotics medications in the last 6 months. * Pregnant/ lactating/ Irregular menstrual cycle/ menopausal. * Currently following a formal/ structured weight loss program. * Currently taking fish oil. * Do not have access to smart phone/ computer with internet access. * Exercise ≥ 1 time/week or a moderate-high score on the International Physical Activity Questionnaire. * Feeling uncomfortable riding bike for 30 minutes. * Claustrophobic or unable to stay under the hood for metabolic testing.

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Conditions

The condition(s) this trial relates to.

Dyslipidemias hyperlipidemia hypertriglyceridemia Inflammation inflammatory disease inherited lipid metabolism disorder Insulin Resistance Obesity obesity disorder prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dyslipidemias Human microbiome Inflammation Insulin resistance Obesity

Contacts and locations

Locations

  • Texas Tech Kinesiology Building

    Lubbock, Texas, 79406, United States

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