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Walk away from memory loss: exercise trial for kidney patients

NCT ID NCT07160959

Prevention Sponsor: Biogem s.c.ar.l. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a simple home exercise program can prevent memory and thinking problems from getting worse in people with advanced chronic kidney disease (stages 4-5). 124 participants will either do low-intensity walking and strength exercises or receive standard care. The goal is to find an easy, drug-free way to protect brain health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
home-based low-intensity interval exercise program (walking and strength training)
What this could lead to
If it works, this could offer a simple, drug-free way to protect brain function in people with advanced kidney disease.
What could go wrong
This is a small, early-stage trial (124 people) testing a behavioral intervention, so results may not be generalizable. Exercise adherence at home may be low, and cognitive benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 124 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * CKD at KDOQI stage 4-5 * concomitant MCI (MOCA - MMSE (17 \< MoCA \< 26) or (16 \< MMSE \< 24) Exclusion Criteria: * Absolute contraindication to exercise training (e.g. unstable angina, major amputation, severe heart failure, etc.) * Known life expectancy \< 6-month * Uncorrected anemia (Hb \<9 g/dl) * Non-provision of informed consent

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Cognitive Dysfunction end stage renal failure Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney disease (stages 4 and 5) Mild cognitive impairment (MCI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites in 6 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Assistance Publique - Hôpitaux de Paris (AP-HP), Division of Geriatry

    Paris, France

  • Biogem

    Ariano Irpino, 83031, Italy

  • Lithuanian University of Health Sciences

    Kaunas, Lithuania

  • Medical University of Warsaw, Department of Nephrology, Dialysis and Internal Medicine

    Warsaw, Poland

  • University Medical Center Groningen, Department of Nephrology

    Groningen, Netherlands

  • University of Zurich

    Zurich, Switzerland

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