Could pistachios be safe for failing kidneys? trial tests a forbidden snack
NCT ID NCT07815600
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
People with advanced chronic kidney disease often avoid nuts because of concerns about phosphorus and potassium. Researchers at Shahid Beheshti University of Medical Sciences are testing whether a daily 30-gram serving of pistachios, added to a standard kidney diet, changes levels of phosphorus, parathyroid hormone, and other minerals in the blood and urine. The trial enrolls 20 adults with stage 4 or 5 kidney disease who are not on dialysis. Each participant follows both a pistachio diet and a control diet for four weeks, with a four-week break in between, so researchers can compare the two within the same person.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pistachios added to a kidney-friendly diet
- What this could lead to
- If pistachios do not raise phosphorus or parathyroid hormone, this could give people with advanced kidney disease a heart-healthy snack option that current diet rules often discourage.
- What could go wrong
- The trial is very small, with 20 participants, and lasts only a few weeks, so it cannot show long-term effects on heart health or kidney outcomes. Pistachios are also a common allergen, and the diet still requires careful monitoring.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
Mar 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 * Stage 4 or 5 non-dialysis CKD, defined as an estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73 m2 Exclusion Criteria: * Unwillingness or inability to provide informed consent. * History of renal replacement therapy (maintenance dialysis or renal transplantation). * Baseline hyperphosphatemia. * Known allergy to pistachios. * Pregnancy or lactation. * Active malignancy under treatment. * Consumption of \<80% of the provided pistachio ration during the intervention period.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Chronic kidney disease (stages 3B-5) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Keshavarz Boulevard, end of Royan Alley - Royana Dead End - Amir Ali Clinic
Tehran, Tehran Province, Iran
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A conversation starter for kidney care: can a checklist give older patients a stronger voice?
- Choosing dialysis or transplant: does a shared approach lead to better decisions?
- A new app maps kidney-friendly meals for dining out in singapore
- Can digital tools and training help more kidney patients get transplants?
- Can a new pill help diabetics with kidney disease control blood sugar?
- Can light therapy speed up dialysis fistula healing?