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Can exercise rewind the clock? study tests Aging's impact on fitness gains

NCT ID NCT06471569

First seen Nov 16, 2025 · Last updated Jun 23, 2026 · Updated 32 times

Summary

This study looks at how aging changes the way older adults respond to exercise. Researchers will have 26 people who previously completed a structured exercise program do a 6-month aerobic workout. They will measure changes in insulin sensitivity and heart fitness to see if age affects how much people benefit from exercise.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke Center for Living

    Durham, North Carolina, 27705, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aerobic exercise

What this could lead to

If successful, this study could help design better exercise programs tailored to older adults with conditions like prediabetes or obesity.

What could go wrong

This is a small pilot study with only 26 participants, so results may not apply to everyone. The trial is currently suspended, which may delay findings.

Conditions

The condition(s) this trial relates to.

cardiovascular disorder Insulin Resistance Motor Activity Obesity prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.