Can acupuncture spark awareness in Brain-Injury patients?
NCT ID NCT07551076
First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 4 times
Summary
This study will test whether electroacupuncture at specific points on the hands can help people with long-term disorders of consciousness, such as a vegetative state or minimally conscious state. Researchers plan to enroll 66 participants and use standard consciousness scales to measure any improvements. The goal is to see if this traditional Chinese medicine technique can safely and effectively promote arousal.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electroacupuncture at Jing-Well points
- What this could lead to
- If it works, this could offer a safe, non-invasive way to help some patients with chronic disorders of consciousness regain awareness.
- What could go wrong
- This is a small, early-stage study with no control group, so results may not be conclusive. The treatment may not work for all patients, and benefits could be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 72 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meet the above diagnostic criteria for pDoC and be diagnosed as Vegetative State (VS) / Unresponsive Wakefulness Syndrome (UWS) or Minimally Conscious State (MCS) based on at least two assessments using the Coma Recovery Scale-Revised (CRS-R); * First occurrence of a clearly identified acquired brain injury resulting in pDoC, including traumatic brain injury, intracerebral hemorrhage, or cerebral infarction, with complete clinical records available; * No obvious hydrocephalus or severe cerebral atrophy, with a disease course ranging from 28 days to 6 months; * Aged between 18 and 72 years, with no gender restriction; * No significant cognitive, hearing, or visual impairment prior to onset; * Normal premorbid communication ability and no history of neurological or psychiatric disorders that may affect consciousness assessment; * Clinically stable and not having participated in other clinical trials within the past 1 months; * Written informed consent obtained from the patient's legally authorized representative. Exclusion Criteria: * Patients with consciousness disturbance of unknown etiology; * Presence of neurodegenerative diseases, intracranial infections, or brain tumors; * Severe cardiac, pulmonary, hepatic, or renal dysfunction, or other serious comorbidities that may increase the risk associated with the intervention; * Hemodynamic or respiratory instability, including resting heart rate \<40 beats/min or \>130 beats/min, oxygen saturation \<88%, systolic blood pressure \>180 mmHg or \<90 mmHg, or mean arterial pressure \<65 mmHg or \>110 mmHg; * Presence of implanted electronic devices that may affect the safety of electrical stimulation, such as cardiac pacemakers or spinal cord stimulators; * History of long-term dependence on psychoactive medications; * Presence of skin lesions, marked hypersensitivity, or other contraindications at the stimulation sites that preclude the use of hand twelve Jing-well point electrical stimulation; * Any other factors that may affect assessment and treatment; * Patients with uncontrolled epileptic seizures or status epilepticus; * Pregnant female patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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