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Engineered immune cells take on deadly brain tumors in first human trial

NCT ID NCT06186401

First seen Feb 13, 2026 · Last updated Jun 18, 2026 · Updated 22 times

Summary

This early-stage trial tests a new treatment for glioblastoma, an aggressive brain cancer. Researchers take a patient's own immune cells, modify them in the lab to better recognize and attack the tumor, and then infuse them back. The study involves 20 adults whose tumors have a specific marker (EGFRvIII) and aims to find the safest dose and check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.