EGFR GENE MUTATION
Clinical trials for EGFR GENE MUTATION explained in plain language.
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New drug cocktail shows promise for tough lung cancer
Disease control Recruiting nowThis study tests a combination of two drugs (Sacituzumab Tirumotecan and Furmonertinib) in 25 adults with advanced non-squamous non-small cell lung cancer that has an EGFR gene mutation and has worsened after standard treatments. The goal is to see if the combo can shrink tumors …
Matched conditions: EGFR GENE MUTATION
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 26, 2026 05:40 UTC
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Engineered t cells take on deadly brain tumors in first human test
Disease control Recruiting nowThis early-stage trial tests a new cell therapy called E-SYNC CAR T cells for people with a specific form of glioblastoma, an aggressive brain cancer. The treatment uses a patient's own immune cells, modified in a lab to better recognize and attack the tumor. About 20 adults will…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE1 • Sponsor: Hideho Okada, MD, PhD • Aim: Disease control
Last updated May 26, 2026 05:37 UTC
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Heart drug may help radiation zap brain tumors in lung cancer patients
Disease control Recruiting nowThis study tests whether adding a nitroglycerin patch (a heart medication) to standard radiation therapy can better shrink brain tumors in people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the brain. About 74 adults will be ran…
Matched conditions: EGFR GENE MUTATION
Phase: NA • Sponsor: Instituto Nacional de Cancerologia de Mexico • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Simple blood test could spot hidden lung cancer in high-risk groups
Diagnosis Recruiting nowThis study is testing a new blood test that looks for signs of a specific type of lung cancer (EGFR-positive) in healthy Asian and Latinx adults who are at risk but cannot get standard lung cancer screening. The test measures DNA fragments in the blood. Researchers will enroll 1,…
Matched conditions: EGFR GENE MUTATION
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated May 26, 2026 05:36 UTC
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Scientists rebiopsy lung tumors to catch resistance early
Knowledge-focused Recruiting nowThis study looks at why some lung cancers stop responding to targeted therapy. Researchers will take small tumor samples before and after treatment to find early signs of resistance. The goal is to develop better drug combinations that can overcome resistance. About 100 adults wi…
Matched conditions: EGFR GENE MUTATION
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 05:38 UTC