EGFR GENE MUTATION
Clinical trials for EGFR GENE MUTATION explained in plain language.
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New hope for drug-resistant lung cancer: combo therapy enters trial
Disease control Recruiting nowThis study tests a combination of two drugs (Sacituzumab Tirumotecan and Furmonertinib) in 25 people with advanced non-squamous non-small cell lung cancer that has an EGFR gene mutation and has stopped responding to standard treatments. The goal is to see if the combo can shrink …
Matched conditions: EGFR GENE MUTATION
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Heart drug could boost radiation for brain tumors in lung cancer patients
Disease control Recruiting nowThis phase III trial tests whether adding nitroglycerin patches to standard radiation therapy helps shrink brain tumors better than radiation alone in people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer). 74 participants will receive either radiatio…
Matched conditions: EGFR GENE MUTATION
Phase: NA • Sponsor: Instituto Nacional de Cancerologia de Mexico • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Engineered immune cells take on deadly brain tumors in first human trial
Disease control Recruiting nowThis early-stage trial tests a new treatment for glioblastoma, an aggressive brain cancer. Researchers take a patient's own immune cells, modify them in the lab to better recognize and attack the tumor, and then infuse them back. The study involves 20 adults whose tumors have a s…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE1 • Sponsor: Hideho Okada, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New blood test aims to catch lung cancer early in underserved groups
Diagnosis Recruiting nowThis study is testing a new blood test that looks for pieces of tumor DNA (EGFR mutations) to screen for lung cancer in healthy people aged 50-80 who are of East Asian, Southeast Asian, or Hispanic/Latinx background and do not currently smoke. The goal is to find lung cancer earl…
Matched conditions: EGFR GENE MUTATION
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Scientists peek inside lung tumors to outsmart drug resistance
Knowledge-focused Recruiting nowThis study looks at why some lung cancer cells survive targeted treatment. Researchers will take small tissue samples (biopsies) from 100 patients before and two weeks after starting therapy. By comparing the samples, they hope to find early signs of resistance and identify ways …
Matched conditions: EGFR GENE MUTATION
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC