EGFR GENE MUTATION
Clinical trials for EGFR GENE MUTATION explained in plain language.
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Early trial tests drug cocktails to target advanced cancers
Disease control OngoingThis early-stage study is testing the safety and best doses of a drug called neratinib when given with one of three other drugs (everolimus, palbociclib, or trametinib). It is for adults with advanced solid tumors that have specific genetic mutations and have stopped responding t…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New drug duo aims to outsmart advanced lung cancer
Disease control OngoingThis study is testing if adding a drug called ramucirumab to a standard targeted therapy (osimertinib) works better for controlling advanced lung cancer with a specific genetic change (EGFR mutation). It will involve about 160 adults who have not yet taken this type of targeted d…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE2 • Sponsor: Xiuning Le • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Scientists test drug combo to outsmart aggressive lung cancer
Disease control OngoingThis study is testing if a targeted drug (osimertinib) works better alone or combined with two chemotherapy drugs for people with advanced non-small cell lung cancer who have two specific genetic changes (EGFR and TP53 mutations). It aims to see which approach better controls the…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE3 • Sponsor: Li Zhang, MD • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Doctors test Immune-Boosting drugs with radiation to fight lung cancer
Disease control OngoingThis early-stage study is testing whether two immunotherapy drugs (ipilimumab and nivolumab) can be safely combined with radiation therapy for patients with stage II or III non-small cell lung cancer. The goal is to see if this combination helps the immune system attack the cance…
Matched conditions: EGFR GENE MUTATION
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Smartphones and fitbits track cancer drug side effects in real-time
Knowledge-focused OngoingThis study is testing a remote monitoring system to better track symptoms and side effects in lung cancer patients taking oral targeted therapy pills. Participants use a smartphone app, a Fitbit watch, and a smart pill bottle cap for up to 24 weeks. The goal is to see if this sys…
Matched conditions: EGFR GENE MUTATION
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC