MGMT-UNMETHYLATED GLIOBLASTOMA
Clinical trials for MGMT-UNMETHYLATED GLIOBLASTOMA explained in plain language.
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Engineered t cells take on deadly brain tumors in first human test
Disease control Recruiting nowThis early-stage trial tests a new cell therapy called E-SYNC CAR T cells for people with a specific form of glioblastoma, an aggressive brain cancer. The treatment uses a patient's own immune cells, modified in a lab to better recognize and attack the tumor. About 20 adults will…
Matched conditions: MGMT-UNMETHYLATED GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Hideho Okada, MD, PhD • Aim: Disease control
Last updated May 26, 2026 03:44 UTC
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Experimental combo therapy targets aggressive brain cancer in early trial
Disease control Recruiting nowThis study tests whether adding two experimental drugs, DB107-RRV and DB107-FC, to standard treatment (radiation and chemotherapy) helps people with newly diagnosed high grade glioma, a fast-growing brain tumor. About 70 adults aged 18-75 will receive the drugs during surgery and…
Matched conditions: MGMT-UNMETHYLATED GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 03:30 UTC
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Could a new drug combo extend lives in aggressive brain cancer?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…
Matched conditions: MGMT-UNMETHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New combo therapy aims to outsmart deadly brain cancer
Disease control Recruiting nowThis study tests whether adding the drug WP1066 to standard radiation therapy can help people with a newly diagnosed, aggressive brain cancer called glioblastoma. The drug targets a protein that helps the tumor grow and hide from the immune system. About 39 adults will take part …
Matched conditions: MGMT-UNMETHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated May 19, 2026 11:48 UTC