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Wisdom tooth woes? a simple injection might ease pain and swelling

NCT ID NCT07258498

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a single injection of the steroid dexamethasone, given under the gum after wisdom tooth removal, can reduce pain, swelling, and jaw stiffness. 70 adults aged 18-45 with impacted lower wisdom teeth took part. The goal was to help patients get back to daily life sooner after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

70 people

The number who actually took part.

Started

Oct 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cases of impacted mandibular third molar according to Pell and Gregory classification (class l, 2. 3 and A. B, C) * Both genders (male and female) * Age limit: 18 - 45 years Exclusion Criteria: * Patients with pericoronitis. * Patients with known allergy to corticosteroids. * Medically compromised patients. * Current pregnancy. * Lactating women. * Use of medication by the patients that could interfere with the healing process.

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Conditions

The condition(s) this trial relates to.

Pain Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • PAEC General Hospital, Islamabad

    Islamabad, Capital, 44000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.