Vitamin c may help preserve jawbone after tooth pull
NCT ID NCT06569264
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding vitamin C to a dentin graft helps preserve the width of the jawbone after a tooth is removed. 26 adults needing a single tooth extraction will receive either the graft with vitamin C or the graft alone. The main goal is to see if vitamin C reduces bone shrinkage, which could improve the site for future dental implants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- autogenous demineralized dentin graft with i-PRF and vitamin C
- What this could lead to
- If it works, this could improve bone healing after tooth extraction, making it easier to place dental implants later.
- What could go wrong
- This is a small, early-stage trial with only 26 participants, so results may not apply to everyone. Adding vitamin C may not provide extra benefit over the graft alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 26 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Inclusion criteria: * ≥ 18 years of age. * Single extraction of non-molar teeth with periodontally healthy adjacent teeth. * Non-contributory medial history. * Non- restorable teeth indicated for extraction. * Requiring alveolar preservation after tooth extraction prior to placement of dental implant. * Participants that are eligible for immediate implantation, yet having factors that are hindering these patients from immediate placement of an implant at the time of extraction (ex: Financial related factors - psychological psychological factors - time related factors). * Cooperative patients who are willing to commit for 3 months follow up. Exclusion Criteria: * Pregnant female. * Acute infection at extraction site. * Systemic conditions affecting healing (e.g., diabetes, medications as bisphosphonates...) * A participant who had radiotherapy or chemotherapy. * Psychiatric patient, or with a learning disability, or unable to give consent.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry, Cairo University
RECRUITINGCairo, Egypt
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Other studies related to the condition(s) this trial covers.
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- Tooth-Derived graft material tested for better jawbone preservation
- Fish oil might help keep your jawbone strong after a tooth pull
- Your own tooth and blood may help preserve jawbone after extraction