Your own tooth and blood may help preserve jawbone after extraction
NCT ID NCT06275490
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two ways to preserve bone after a tooth is pulled in the front of the mouth. One method uses a block made from the patient's own tooth and blood components, while the other uses a standard bone graft material. Twenty healthy adults with a non-restorable front tooth took part. The goal was to see which method better maintains bone shape and quality for future dental implants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Partially demineralized dentin block mixed with L-PRF (platelet- and leukocyte-rich fibrin)
- What this could lead to
- If this method works, it could offer a way to preserve bone after tooth extraction using the patient's own tooth and blood, potentially improving outcomes for future dental implants.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply to everyone. The approach is experimental and may not be better than existing methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥18 years. * Healthy individuals with no medical history. * Patients who have a single non-restorable tooth in the esthetic zone. * Post-extraction socket with four bone walls (Type I Extraction socket). * Patients capable of understanding or signing the informed consent form before surgery and capable of meeting oral cleaning requirements for implant placement. Exclusion Criteria: * Systemic disease that might impair bone metabolism, antiresorptive therapy (as bisphosphonates),pregnancy, psychiatric conditions. * Heavy smokers (\> 10 cigarettes) * The presence of acute or chronic infection at the site of tooth extraction with lack of treatment for periodontal disease, or x-rays showing loss of alveolar bone on the adjacent teeth.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of dentistry Cairo University
Cairo, Elmanil, 4240101, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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