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Cranberry pills take on antibiotics in UTI prevention showdown

NCT ID NCT03522961

First seen Nov 17, 2025 · Last updated Jun 22, 2026 · Updated 33 times

Summary

This study compares cranberry tablets to the antibiotic nitrofurantoin for preventing urinary tract infections (UTIs) in women after pelvic surgery. About 142 women having surgery for pelvic organ prolapse or urinary incontinence will be randomly assigned to take either cranberry capsules or nitrofurantoin for a short time after their operation. The goal is to see if the natural cranberry option works as well as the standard antibiotic to keep UTIs away.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cranberry tablets and nitrofurantoin

What this could lead to

If cranberry tablets work as well as nitrofurantoin, women could have a natural, antibiotic-free option to prevent UTIs after pelvic surgery.

What could go wrong

This is a small, single-center trial with 142 participants. Cranberry may not be as effective as antibiotics, and results may not apply to all women.

Conditions

The condition(s) this trial relates to.

pelvic organ prolapse Urinary Incontinence urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.