Pelvic organ prolapse

This trial tests a new surgical method to treat pelvic organ prolapse in women having a hysterectomy. The surgeon uses special ligaments to support the vaginal vault. Ten women will take part, and the study will measure how much the prolapse improves.

This study compares a new surgical technique called transobturator cystocele repair (TOCR) to the standard anterior repair for fixing a cystocele, a type of pelvic organ prolapse where the bladder bulges into the vagina. About 592 women aged 50 and older with at least stage 2 pro…

This study tests whether a pelvic floor muscle training program, delivered through a mobile app, can reduce urinary incontinence and other pelvic floor disorders after childbirth. About 734 first-time pregnant women will either follow the app-based training or receive standard ca…

This study tests whether a patient reminder system before a urodynamics procedure (a test for bladder function) helps women with pelvic organ prolapse or urinary incontinence. Researchers compare a group that receives reminders to a historical group that did not, looking at proce…

This study tests a telehealth program designed to help Latina patients feel more prepared for urogynecologic surgery, such as procedures for incontinence or pelvic organ prolapse. The program is being developed with input from patient partners and uses human-centered design. Rese…

This study tests whether a 6-week home exercise program (focused on relaxing and stretching the pelvic floor) can improve physical functioning after vaginal prolapse surgery. About 92 women aged 60-79 will be randomly assigned to either do the exercises or receive usual care. Res…

This study tests whether virtual group counseling sessions help patients feel more prepared and satisfied before pelvic organ prolapse surgery, compared to standard individual phone calls. About 106 adults scheduled for surgery at Cleveland Clinic will fill out surveys before and…

This study compares two procedures—a sling or a bulkamide injection—to treat stress urinary incontinence in women who are also having vaginal prolapse repair. About 476 participants will be randomly assigned to one of the two treatments and followed for 24 months. The goal is to …

This trial studies 88 women undergoing vaginal surgery for pelvic organ prolapse. Half will take senna pills and half will use bisacodyl suppositories after surgery. Researchers will measure how quickly each group has their first bowel movement and how satisfied they are with the…

This study tests whether adding hypopressive exercises to standard pelvic floor muscle training helps women aged 45-65 with mild pelvic organ prolapse. About 46 married, postmenopausal women with stage I or II prolapse will be split into two groups: one doing standard exercises a…

This study compares two ways of doing a common surgery for pelvic organ prolapse and stress incontinence. Doctors want to know if placing a small mesh sling before or after lifting the vagina leads to better bladder control and happier patients. About 110 women having robotic sur…

This study compares two types of laparoscopic pectopexy surgery for women with pelvic organ prolapse after hysterectomy. One method uses a mesh to support the vagina, while the other does not. The goal is to see which approach leads to fewer relapses and better quality of life, w…

This study is testing whether a remote, video-based pelvic floor muscle therapy program is easy to use and practical for patients with pelvic floor disorders like prolapse, incontinence, or bowel issues. Twenty participants will follow an 8-week online course at home. The main go…

This study looks at whether a common surgery for pelvic organ prolapse can be performed without an overnight hospital stay. About 80 women with symptomatic prolapse will receive laparoscopic surgery with or without robotic help. The goal is to see if same-day discharge is safe an…

This study will follow 1,360 Chinese women with pelvic floor disorders, such as postpartum weakness or mild to moderate prolapse, as they receive one of three rehabilitation treatments: pelvic floor muscle training, biofeedback electrical stimulation, or magnetic stimulation. Res…

This study is a long-term registry that will follow 1,000 women who receive pelvic mesh products for stress urinary incontinence or pelvic organ prolapse. Researchers will track how well the mesh works and any complications over 5 to 10 years. The goal is to gather real-world dat…

This study follows 288 women recovering from pelvic organ prolapse surgery. Participants wear a wrist accelerometer and complete a daily recovery questionnaire. Some receive routine recovery instructions, while others get an exercise-focused plan. The goal is to see which approac…

This study looks at whether using ultrasound imaging and muscle activity sensors together can help women with weak pelvic floor muscles stick with their exercises and get better results. About 70 women will try different feedback methods during training. The goal is to find the b…