PELVIC ORGAN PROLAPSE
Clinical trials for PELVIC ORGAN PROLAPSE explained in plain language.
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New device aims to prevent pelvic muscle tears during childbirth
Disease control OngoingThis study tests a device called Materna Prep that gently stretches the vagina and pelvic floor before delivery. The goal is to see if it reduces muscle injuries during birth. About 420 women having their first vaginal birth will be randomly assigned to use the device or receive …
Matched conditions: PELVIC ORGAN PROLAPSE
Phase: NA • Sponsor: Materna Medical • Aim: Disease control
Last updated May 26, 2026 05:37 UTC
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Mesh vs sutures: which surgery works best for pelvic organ prolapse?
Disease control OngoingThis study compares two vaginal surgery methods for pelvic organ prolapse (when organs like the bladder or uterus drop into the vagina). One method uses synthetic mesh, the other uses sutures. 358 women will be randomly assigned to one of the two surgeries and followed for 2 year…
Matched conditions: PELVIC ORGAN PROLAPSE
Phase: NA • Sponsor: University of British Columbia • Aim: Disease control
Last updated May 26, 2026 05:32 UTC
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Mesh surgery offers hope for women with severe prolapse
Disease control OngoingThis study tested a new keyhole surgery technique using an inverted T-shaped mesh to repair advanced uterine and anterior vaginal prolapse in 67 women who wanted to keep their uterus. The surgery aims to improve pelvic organ support and reduce symptoms like discomfort and pressur…
Matched conditions: PELVIC ORGAN PROLAPSE
Sponsor: Chung Shan Medical University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New stitch device aims to fix pelvic organ prolapse
Disease control ENROLLING_BY_INVITATIONThis study is testing a new device called i-Stitch for women having surgery to fix pelvic organ prolapse (when organs like the bladder or uterus drop into the vagina). About 100 women will get the device during a standard repair procedure. The goal is to see if the device is safe…
Matched conditions: PELVIC ORGAN PROLAPSE
Sponsor: A.M.I. Agency for Medical Innovations GmbH • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Cranberry vs. antibiotic: which prevents Post-Surgery UTIs better?
Prevention OngoingThis study compares cranberry capsules to the antibiotic nitrofurantoin for preventing urinary tract infections (UTIs) after surgery for pelvic organ prolapse or urinary incontinence. About 142 women will be randomly assigned to take either cranberry or nitrofurantoin for 28 days…
Matched conditions: PELVIC ORGAN PROLAPSE
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated May 22, 2026 14:04 UTC
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Laser therapy for pelvic organ prolapse trial pulled before start
Symptom relief TerminatedThis study planned to test a laser treatment for women with mild to moderate pelvic organ prolapse who had not been helped by other treatments. Participants would have received either real laser therapy or a sham procedure to see if the laser improved symptoms and quality of life…
Matched conditions: PELVIC ORGAN PROLAPSE
Phase: NA • Sponsor: Hampshire Hospitals NHS Foundation Trust • Aim: Symptom relief
Last updated May 26, 2026 05:37 UTC
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New collapsible pessary could free women from frequent doctor visits
Symptom relief ENROLLING_BY_INVITATIONThis study tests a new collapsible pessary (Reia) for women with pelvic organ prolapse. The goal is to see if it allows patients to care for their prolapse on their own, instead of needing to visit a provider 2-4 times per year. About 120 current pessary users will try the device…
Matched conditions: PELVIC ORGAN PROLAPSE
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Prolapse surgery study digs into costs and scar satisfaction
Knowledge-focused OngoingThis study looks at the costs during surgery and how satisfied patients are with their scars after two types of prolapse repair (robotic vs. open surgery). Researchers will track expenses like operating time and supplies, and ask 80 women to rate their scars and overall surgical …
Matched conditions: PELVIC ORGAN PROLAPSE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC