New study to reveal hidden effects of Weight-Loss drug on joints and heart

NCT ID NCT07567378

Not yet recruiting Knowledge-focused Sponsor: JULIO GRANADOS MONTIEL Source: ClinicalTrials.gov ↗

First seen May 07, 2026 · Last updated Jun 17, 2026 · Updated 9 times

Summary

This study observes 30 adults in Mexico who are already taking tirzepatide (a diabetes/weight-loss drug) to see how it impacts knee cartilage, heart fat, and body composition over 52 weeks. Researchers will use advanced MRI and CT scans, along with blood tests and body measurements, to understand the drug's effects beyond weight loss. No new treatments are given; participants continue their regular care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Locations

IMSS Clínica Río Magdalena

Mexico City, Mexico City, 01090, Mexico

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome atrial fibrillation coronary artery disorder diabetes mellitus heart failure metabolic dysfunction-associated steatotic liver disease metabolic syndrome X Obesity obesity disorder osteoarthritis osteoarthritis, knee pericardium disorder psoriatic arthritis Sarcopenia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) CORONARY ARTERY DISEASE DIABETES (DM) HEART FAILURE INSULIN RESISTANCE SYNDROME KNEE METABOLIC SYNDROME NON ALCHOLIC FATTY LIVER DISEASE OBESITY (DISORDER) OSTEOARTHITIS PERICARDIUM PRESERVED EJECTION FRACTION PSORIATIC ARTHRITIS SARCOPENIA TYPE 2 DIABETES MELLITUS (T2DM)