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Could a simple supplement heal stomach damage from h. pylori?

NCT ID NCT07179237

Disease control Sponsor: Catalysis SL Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 2 trial tests whether a dietary supplement called Carminal can help heal the stomach lining and reduce symptoms in people with H. pylori gastritis. Eighty adults will receive either Carminal or a placebo alongside standard antibiotic therapy, followed by 12 weeks of continued supplement use. The study measures symptom improvement and stomach healing through endoscopy and biopsies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Carminal (dietary supplement containing aloe vera, olive extract, glutamic acid, and zinc)
What this could lead to
If it works, this could provide a safe, natural supplement to help heal stomach damage and reduce symptoms after H. pylori treatment.
What could go wrong
This is a small Phase 2 trial with only 80 participants, so results may not apply to everyone. As a dietary supplement, its effects may be modest and not replace standard medical therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years or older * Patients with clinical symptoms of dyspepsia * Patients diagnosed with Helicobacter pylori positive gastritis, confirmed by upper endoscopy with histology * Patients who give written informed consent to participate in the study Exclusion Criteria: * Patients with peptic ulcer disease * Patients with previous gastric surgery * Patients with current malignancy or the history of any previous malignancies * Patients taking another investigational product, or have taken any investigational product in the last year * Patients with known hypersensitivity to any ingredients found in the investigational product. * Decompensated intercurrent illnesses, including: active infections, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, liver disease, and psychiatric illnesses that may limit adherence to the requirements of the clinical trial, or any other special condition that, according to the physician's judgement, jeopardises the patient's health or life during participation in the trial. * Planned pregnancy for the duration of trial, pregnancy, breast feeding, or postpartum period. * Patients with human immunodeficiency virus (HIV).

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Conditions

The condition(s) this trial relates to.

bacterial gastritis gastritis Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gastric mucosal lesion Gastritis associated with helicobacter pylori H pylori eradication H pylori gastritis H.pylori infection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinical Center of Serbia - Clinic for Gastroenterohepatology

    RECRUITING

    Belgrade, Central Serbia, 11000, Serbia

  • Zvezdara Medical Center - Department of Gastroenterology

    RECRUITING

    Belgrade, Central Serbia, 11000, Serbia

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