New stomach bug treatment shows promise in 14-Day trial
NCT ID NCT06682533
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how well a 14-day course of tegoprazan (a stomach acid reducer) combined with two antibiotics works to clear H. pylori infection. About 200 adults who need a stomach scope will take the treatment, and researchers will check if the bacteria are gone using a breath test. The goal is to see if this approach is effective and tolerable, especially when adding bismuth to boost success rates.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
H. pylori-infected patients
- Ages
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20 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Gastroscopy can be performed * H. pylori test and pathological analysis can be performed Exclusion Criteria: * Age \< 20 or \> 80 years * Anemia (serum hemoglobin level \< 10 g/dL) * Severe systemic disease * Advanced chronic liver disease * Use of certain medications, including proton pump inhibitors, H2- receptor antagonists, or antibiotics * History of H. pylori eradication * Drug allergy to antibiotics * History of gastric surgery * Recent history of upper gastrointestinal bleeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Digestive Disease Center, Soonchunhyang University Hospital
RECRUITINGSeoul, 04401, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New Two-Drug combo shows promise against stomach bug
- Which test is better for detecting h. pylori?
- Stomach bug treatment may lower bleeding risk for heart patients
- Scientists map h. Pylori's resistance to antibiotics
- Argon plasma zaps stomach bugs in new trial
- Can a daily yogurt beat stomach bugs in kids?