Could a zappy headband ease shingles nerve pain?
NCT ID NCT07352553
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive brain stimulation device can reduce the persistent nerve pain that sometimes follows a shingles infection. Researchers will compare real stimulation to a sham (fake) procedure in 94 adults who have had pain for at least 3 months. Participants receive 30-minute sessions daily for 10 days, and the team will track changes in pain, sleep, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- non-invasive transcranial electrical stimulation
- What this could lead to
- If it works, this could offer a drug-free option to reduce stubborn nerve pain after shingles.
- What could go wrong
- This is a small, early-stage trial with no phase assigned. The sham control means some may not benefit, and results may not apply to everyone with postherpetic neuralgia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 94 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * Diagnosis of postherpetic neuralgia (PHN) with disease duration ≥ 3 months. * NRS pain score ≥ 4. * Willing to receive the intervention and able to provide written informed consent. Exclusion Criteria: * Contraindications to electrical stimulation (e.g., intracranial metal implants, cardiac pacemaker). * History of epilepsy, severe psychiatric disorder, or cognitive impairment. * Pregnant or breastfeeding women. * Unable to comply with the intervention procedures and follow-up assessments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tongji hospital
Wuhan, Hubei, 430030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New gel promises shingles pain relief in minutes
- Can nerve zapping predict who gets pain relief from shingles?
- New hope for shingles pain sufferers: drug trial underway
- New drug shows promise for shingles nerve pain
- Shingles pain relief showdown: nerve block vs radiofrequency
- Zapping away shingles pain: new trial tests pulsed radiofrequency