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Teen obesity and blood sugar changes may reshape the brain, study warns

NCT ID NCT05277558

First seen Jan 09, 2026 · Last updated Jun 18, 2026 · Updated 28 times

Summary

This study looks at how being overweight or having early signs of type 2 diabetes affects the brains of teenagers aged 12 to 17. Researchers will use brain scans and memory tests to see which factors—like insulin resistance or inflammation—are most linked to changes in brain structure and thinking skills. The goal is to understand how these risks impact brain development over time, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Inflammation inflammatory disease Insulin Resistance microvascular complications of diabetes, susceptibility Obesity obesity disorder Overweight Pediatric Obesity type 1 diabetes mellitus type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.