OBESITY, CHILDHOOD

This study compares ear acupressure (using small seeds on ear points) with intermittent carbohydrate restriction to help obese children lose weight. The trial includes 240 children who have specific traditional Chinese medicine symptoms. Researchers will measure changes in body w…

This study looks at whether adding extra fiber to metformin treatment works better than either alone for teens aged 12-18 with severe obesity and insulin resistance. Over 12 months, researchers will measure changes in insulin resistance, weight, and body composition. The goal is …

This study tests a program called LEADS for African American families with overweight teens. The program teaches coping skills like mindfulness and positive parenting to help teens be more active. Researchers will measure if it increases daily exercise and improves health over 6 …

This study tests a program called Food-Body-Mind for 800 preschoolers aged 3-5 from low-income families in Head Start. The program aims to improve children's mental health, social skills, and reduce obesity by teaching healthy eating, physical activity, and emotional coping. Rese…

This study tests a program called CHAMPION that helps overweight children with asthma manage their weight and breathing. Researchers want to see if doing the program online works as well as meeting in person. About 500 children aged 4 to 17 with asthma and a BMI in the 85th perce…

This study tests whether an 8-week whole foods diet can reduce body fat in 60 adolescents aged 10-18 with obesity. Participants will be randomly assigned to the whole foods diet or a control group. The goal is to see if this approach leads to lower fat mass and healthier eating h…

This study tests a program for low-income Latino families to prevent obesity in infants and toddlers. Half of the 576 participants will get coaching on healthy feeding, sleep, and screen time during doctor visits plus text tips. The other half will get safety and language advice.…

This study compares two approaches to help children ages 6-11 sleep longer: working one-on-one with a nurse on sleep strategies versus receiving educational handouts. About 50 families from Temple Pediatrics will participate. The goal is to see if improving sleep can prevent exce…

This study tests whether blowing balloons can improve lung function and reduce shortness of breath in obese children aged 6 to 12. Thirty-eight kids will either blow balloons or do a simple running exercise. Researchers will measure changes in breathing capacity to see if this fu…

This study will measure blood pressure in over 22,000 children aged 5 to 18 across South Africa. The goal is to create the country's own normal blood pressure charts, since current guidelines are based on children from the US and Europe. This will help doctors correctly diagnose …

This study looks at how being overweight or having early signs of type 2 diabetes affects the brains of teenagers aged 12 to 17. Researchers will use brain scans and thinking tests to see which factors—like insulin resistance or inflammation—are linked to changes in memory, proce…

This study gathers information from 500 children with severe, early-onset obesity to learn which genes may be involved. Researchers will look at genetic test results and track body mass index over time. No treatment or intervention is given—this is purely an observational databas…

This study looks at whether a substance in the blood called 1,5-anhydroglucitol can help measure how well insulin-producing beta cells are working in obese children, with or without type 2 diabetes. Researchers will compare levels of this marker in 50 children aged 12 to 16 who a…

This study looks at why some children are less affected by food advertisements and don't overeat when exposed to them. Researchers will use brain scans and eating tests in 200 children aged 7-9 to find patterns that protect against weight gain. The goal is to understand what make…

This study looks at how eating, physical activity, and sleep habits can reduce the risk of obesity in children ages 5 to 7. Researchers will follow 242 children and their mothers to see which behaviors protect against weight gain, especially in kids from low-income backgrounds. T…