OBESITY, CHILDHOOD

This study tests a telehealth program that coaches parents of children with autism and overweight (ages 6-12) on healthy habits, compared to standard health education. About 140 families will participate. The goal is to see if parent-only training can improve children's weight an…

This study planned to help toddlers with obesity by improving what they eat. Parents would join a free online nutrition program and could also take weight-loss medication. The idea was that helping parents eat better would also improve their toddler's diet and weight. However, th…

This study tests whether a medication called lisdexamfetamine, when combined with healthy lifestyle changes, can help children aged 6 to 12 with severe obesity lose weight. About 44 children will be randomly assigned to receive either the drug or a placebo, along with lifestyle t…

This study tests a family-based weight management program for youth with type 1 diabetes who are overweight or obese, along with one of their parents who is also overweight. The program is adapted from a proven treatment and delivered in a hybrid format. The goal is to help both …

This study tests a practical approach for teens with severe obesity: combining lifestyle counseling with medication. About 120 teens aged 12-17 will receive counseling and a weight-loss drug to see if this combo helps them lose weight more effectively than counseling alone. The g…

This study tests a web-based program that teaches parents skills to help their children—who have survived cancer—eat healthier and be more active. It includes 520 families with children aged 5-14 who are off cancer treatment for at least 6 months and have overweight or obesity. T…

This study tests a postbiotic supplement called ABB C3 in 70 children and teens with obesity. Half take the supplement and half take a placebo for 3 months, with an optional 3-month extension. Researchers will measure body fat, blood sugar, and safety to see if ABB C3 can help ma…

This study looks at whether limiting when children and teens with obesity can eat (time-restricted feeding) helps them lose weight over two months and keep it off. Researchers will also explore how the gut microbiome and body clock might play a role. About 67 participants will be…

This study tests a program called FIT Families, designed to help African American teenagers with obesity and their caregivers make healthier lifestyle changes together. The program is led by community health workers and is tailored to the families' needs. About 360 teens and thei…

This phase 2 study tests whether semaglutide, a once-weekly injection, can help preserve insulin-producing cells and reduce liver fat in 60 obese youth with prediabetes or early type 2 diabetes and fatty liver disease. Participants receive semaglutide or placebo for 6 months, wit…

This study works with childcare centers in Arkansas and Louisiana to stop educators from using feeding practices that can lead to obesity in children ages 3 to 5. Researchers will test strategies to replace these habits with healthier ones. About 2,640 children and their classroo…

This study looks at whether giving extra support to childcare centers that struggle with a healthy eating program can help them stick with it. About 1,850 teachers and staff from Arkansas and Louisiana are taking part. The goal is to see if a flexible, cost-effective approach can…

This study tests a program called 'Healthy Dads, Healthy Kids' adapted for Hispanic families. It aims to help fathers lose weight and increase their children's physical activity to prevent obesity. About 187 fathers and their children (ages 5-11) from the Houston area are taking …

This study tests a family program called Turtle Island Tales for American Indian families living in poverty. The program aims to prevent obesity and cancer by encouraging healthy eating, physical activity, less screen time, and better sleep. About 200 caregivers with children age…

This study tests a family-based program that helps mothers and caregivers feed babies in a healthy, responsive way. Researchers want to see if this approach can improve diet quality and prevent unhealthy weight gain in infants. The study includes 165 mothers and their babies, sta…

This study looks at how emotions, attachment, and feeding work together in mothers and babies during the first year of life. Researchers want to understand why some babies gain weight quickly, which can lead to obesity later. About 250 mother-infant pairs will be observed to see …

This study looks at how changing sleep patterns affects eating behavior and self-control in 120 children who are overweight or at risk for obesity. Researchers will track sleep, brain activity, and real-world eating to understand the link between sleep and weight gain. The goal i…

This study looks at 1000 people who may have a rare genetic form of obesity, like Bardet-Biedl syndrome. Researchers will use genetic testing to find the cause and better understand how these conditions affect the body. The goal is to improve early diagnosis and care for those wi…