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New MRI could replace CT scans for spine imaging

NCT ID NCT06745791

Diagnosis Sponsor: MRIguidance B.V. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new MRI technique called BoneMRI that creates CT-like images of the spine without using radiation. Researchers will compare BoneMRI images to standard CT scans in 450 people who need both scans. If accurate, BoneMRI could allow doctors to diagnose and plan spine treatments using just one safe scan.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
BoneMRI (a special MRI technique that creates CT-like images of bone)
What this could lead to
If successful, BoneMRI could replace CT scans for spine imaging, giving doctors clear bone images without radiation exposure. This could make diagnosis, treatment planning, and surgery safer and more efficient.
What could go wrong
This is a validation study, not a treatment trial. It checks if the new MRI technique is accurate enough. There is no guarantee it will work for all patients or replace standard CT scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 450 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects referred to the radiology department for an MRI and CT scan of the spine having symptoms related to a spine disorder with suspected underlying involvement of osseous structures, will be asked to participate in this study.

Ages

12 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥ 12 years old * Indication for diagnostic MRI of the spine * Indication for diagnostic CT of the spine * Eligible for MRI * Eligible for CT * Written informed consent Exclusion Criteria: * Pregnancy * History of (psychiatric) disorder which causes the patient to be incompetent to make a thought-out decision * claustrophobia * \>3 months between CT and MRI scan

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Conditions

The condition(s) this trial relates to.

bone disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone diseases IMAGE Medical device

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    10 sites in 4 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Amsterdam UMC

    RECRUITING

    Amsterdam, 1105AZ, Netherlands

  • Elisabeth Tweesteden Ziekenhuis

    RECRUITING

    Tilburg, 5022GC, Netherlands

  • Erasmus MC

    RECRUITING

    Rotterdam, 3015 GD, Netherlands

  • Hopital saint joseph

    RECRUITING

    Marseille, 13008, France

  • Kantonsspital st. gallen

    RECRUITING

    Sankt Gallen, 9007, Switzerland

  • Leids universitair medisch center

    NOT_YET_RECRUITING

    Leiden, 2333ZA, Netherlands

  • UMC Utrecht

    RECRUITING

    Utrecht, Utrecht, 3584 CX, Netherlands

  • UZ Gent

    RECRUITING

    Ghent, 9000, Belgium

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

  • VITAZ

    RECRUITING

    Sint-Niklaas, 9100, Belgium

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