Cutting radiation in CT scans: a new test of Ultra-Low-Dose imaging
NCT ID NCT05840003
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether an ultra-low-dose CT scan, using a new image reconstruction algorithm, can produce images good enough for diagnosing lung, abdominal-pelvic, and bone lesions, compared to a standard-dose CT scan. About 116 adults will receive both scans as part of their usual care. The goal is to see if the ultra-low-dose images are of sufficient quality to be used routinely, potentially reducing radiation exposure without compromising diagnostic accuracy.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ultra-Low-Dose thoraco-abdominopelvic computed tomography (CT) scan using the Precise Image reconstruction algorithm
- What this could lead to
- If ultra-low-dose CT scans prove as good as standard scans, patients could undergo imaging with far less radiation exposure, reducing long-term risks.
- What could go wrong
- The trial is relatively small and early, and image quality may not be sufficient for all diagnoses. There is also a risk that the ultra-low-dose scans miss subtle lesions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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116 people
The number who actually took part.
- Started
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Sep 2023
- Finished
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Sep 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient having given free and informed consent. * Patient who has signed the consent form. * Patient affiliated to or beneficiary of a health insurance plan. * Patient with a BMI \< 35 kg/m2 Exclusion Criteria: * Patient participating in research involving human subjects defined as Category 1. * Patient in an exclusion period as determined by another study. * Patient under court protection, guardianship or trusteeship. * Patient unable to give consent. * Patient for whom it is impossible to give informed information. * Pregnant patient. * Patient with a BMI ≥ 35 kg/m2
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU
Nîmes, 30029, France
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