Melanoma drug combo trial halted early – only 5 patients enrolled
NCT ID NCT04527549
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 4 times
Summary
This study tested whether adding hydroxychloroquine (a malaria drug) to standard targeted therapy (dabrafenib and trametinib) could help control advanced melanoma that had spread or could not be removed by surgery. It was designed for people with a specific gene mutation (BRAF V600E/K) and high LDH levels in their blood. The trial was stopped early after enrolling only 5 participants, so the results are limited.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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5 people
The number who actually took part.
- Started
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Jun 2021
- Finished
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Jan 2024
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient must have locally advanced unresectable stage IIIC or stage IV melanoma * Patient must have BRAF V600E or BRAF V600K tumor genotype based on a Clinical Laboratory Improvement Act (CLIA) approved assay * Patient must have serum LDH \> Upper limit of normal per institution standards * Patient must have measurable disease by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1. Baseline measurements of sites of disease must be obtained within 3 weeks prior to study randomization * Patient must have been treated with prior immune checkpoint inhibitor therapy (anti PD-1 antibody, anti-CTLA-4 antibody or a combination regimen including either or both agents) either in the adjuvant or metastatic setting. Patient may have received investigational agents in combination with standard therapy, as long as it was adhering to the timeframes below * Patient must have discontinued active immunotherapy (IL-2, interferon, anti-CTLA-4 antibody, anti-PD-1 antibody etc.) or chemotherapy at least 4 weeks prior to randomization * Patient must have discontinued any oral targeted therapy at least 2 weeks prior to randomization * Patient may have been treated with prior adjuvant therapy including combined BRAF and MEK inhibitor therapy. Patients will be eligible if they tolerated this therapy and did not discontinue the therapy due to toxicity AND \>= 6 months have elapsed since the end of adjuvant BRAF and MEK inhibition. * Patient may have been treated with prior chemotherapy or radiation therapy * Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * All females of childbearing potential must have a blood test or urine study within 14 days prior to randomization to rule out pregnancy. * Women of childbearing potential and sexually active males must not expect to conceive or father children by using accepted and effective method(s) of contraception or abstaining from sexual intercourse for the duration of their participation in the study and for 4 months after the last dose of protocol treatment * Patient must have recovered from clinically significant reversible toxicities from previous treatment prior to randomization. Abnormal laboratory values may be grade 1, as long as they meet the eligibility criteria for organ and marrow function * Patient must be able to swallow and retain oral medication and must not have any clinically significant gastrointestinal abnormalities that may alter absorption such as malabsorption syndrome or major resection of the stomach or bowels * Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible * Absolute neutrophil count \>= 1,500/mcL (obtained =\< 14 days prior to protocol randomization) * Platelets \>= 100,000/mcL (obtained =\< 14 days prior to protocol randomization) * Total bilirubin =\< institutional upper limit of normal (ULN) (obtained =\< 14 days prior to protocol randomization) * Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 3.0 x institutional ULN (obtained =\< 14 days prior to protocol randomization) * Creatinine =\< 1.5 x institutional ULN (obtained =\< 14 days prior to protocol randomization) * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial * For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * Patient with asymptomatic new or progressive brain metastases (active brain metastases) are eligible if the treating physician determines that CNS specific treatment is not required * NOTE: Patient with treated brain metastases are eligible. No brain imaging is required, however, 1 week must elapse after gamma knife therapy. Patient treated with whole brain radiation that have been stable for 2 months are eligible. Patient are excluded if they have leptomeningeal disease or metastases causing spinal cord compression that are symptomatic or untreated or not stable (documented by imaging) for at least 3 months or requiring corticosteroids. Patients on a stable dose of corticosteroids for at least 1 month or who have been off of corticosteroids for at least 1 week are eligible Exclusion Criteria: * Receiving any other investigational anticancer therapy during the period on study or the 4 weeks prior to randomization * Patients received BRAF and MEK inhibitor therapy in the metastatic setting * Patients who are experiencing an objective partial response to immunotherapy at the time of study enrollment * Pregnant or breast-feeding; due to the potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used. A female of childbearing potential is defined as any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months) * A history of interstitial lung disease (ILD) or chronic pneumonitis * NOTE: If there is radiographic evidence of ILD that is clinically insignificant and asymptomatic, the patient would be eligible * Porphyria or psoriasis due to risk of disease exacerbation unless the disease is well controlled and they are under the care of a specialist for the disorder who agrees to monitor the patient for exacerbations * Previously documented retinal vein occlusion * A history or evidence of increased cardiovascular risk including: * Left ventricular ejection fraction (LVEF) \< institutional lower limit of normal measured within 14 days prior to randomization * A QT interval corrected for heart rate using the Bazett's formula \>= 480 msec * Current clinically significant uncontrolled arrhythmias. Exception: Patients with controlled atrial fibrillation for \> 30 days prior to randomization are eligible * Acute coronary syndromes (including myocardial infarction and unstable angina), coronary angioplasty, or stenting within 6 months prior to randomization * Abnormal cardiac valve morphology (\>= grade 2) documented by echocardiogram unless a cardiologist concludes the valve abnormality is not clinically significant. Patients with grade 1 abnormalities (i.e., mild regurgitation/stenosis) are eligible * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better * Serious concurrent infection or medical illness, including psychiatric disorders, which would jeopardize the ability of the patient to receive the treatment outlined in this protocol with reasonable safety * Receiving concurrent therapy for their tumor (i.e. chemotherapeutics or investigational agents). Radiotherapy delivered to palliate pain is allowed as long as it is not targeting a lesion that meets RECIST criteria for progression. Radiation therapy to the surgical bed with gamma knife radiotherapy while on treatment during the first cycle is allowed for small volume surgically resected brain metastases. Gamma knife radiotherapy for known active, asymptomatic small volume central nervous system (CNS) lesions may be performed during the first cycle while on study. Radiotherapy for new CNS lesions identified beyond the first cycle is not allowed on study * Immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to study drug, or excipients or to dimethyl sulfoxide (DMSO) * Prior cytochrome P450 enzyme -inducing anticonvulsant drugs (extended-interval aminoglycoside dosing \[EIADs\]) (i.e. phenytoin, carbamazepine, phenobarbital, primidone or oxcarbazepine) within 4 weeks prior to randomization * Current use of a prohibited medication described in the protocol due to potential drug-drug interaction
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alaska Breast Care and Surgery LLC
Anchorage, Alaska, 99508, United States
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Alaska Oncology and Hematology LLC
Anchorage, Alaska, 99508, United States
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Alaska Women's Cancer Care
Anchorage, Alaska, 99508, United States
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Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124, United States
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Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122, United States
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Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130, United States
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Alegent Health Mercy Hospital
Council Bluffs, Iowa, 51503, United States
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Anchorage Associates in Radiation Medicine
Anchorage, Alaska, 98508, United States
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Anchorage Oncology Centre
Anchorage, Alaska, 99508, United States
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Anchorage Radiation Therapy Center
Anchorage, Alaska, 99504, United States
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Armes Family Cancer Center
Findlay, Ohio, 45840, United States
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Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, 45005-1066, United States
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Bay Area Hospital
Coos Bay, Oregon, 97420, United States
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Beebe Health Campus
Rehoboth Beach, Delaware, 19971, United States
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Beebe Medical Center
Lewes, Delaware, 19958, United States
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Beebe South Coastal Health Campus
Frankford, Delaware, 19945, United States
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Bethesda North Hospital
Cincinnati, Ohio, 45242, United States
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Blanchard Valley Hospital
Findlay, Ohio, 45840, United States
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Broadlawns Medical Center
Des Moines, Iowa, 50314, United States
-
CHI Health Good Samaritan
Kearney, Nebraska, 68847, United States
-
CHI Health Saint Francis
Grand Island, Nebraska, 68803, United States
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CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas, 71913, United States
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Cancer Center at Saint Joseph's
Phoenix, Arizona, 85004, United States
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Carle Cancer Center
Urbana, Illinois, 61801, United States
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Carle Physician Group-Effingham
Effingham, Illinois, 62401, United States
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Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938, United States
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Carle on Vermilion
Danville, Illinois, 61832, United States
-
Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
-
Central Care Cancer Center - Bolivar
Bolivar, Missouri, 65613, United States
-
Central Care Cancer Center - Garden City
Garden City, Kansas, 67846, United States
-
Central Care Cancer Center - Great Bend
Great Bend, Kansas, 67530, United States
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Christiana Care Health System-Christiana Hospital
Newark, Delaware, 19718, United States
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Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania, 19317, United States
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Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, 19801, United States
-
Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015, United States
-
Commonwealth Cancer Center-Corbin
Corbin, Kentucky, 40701, United States
-
Cox Cancer Center Branson
Branson, Missouri, 65616, United States
-
CoxHealth South Hospital
Springfield, Missouri, 65807, United States
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Creighton University Medical Center
Omaha, Nebraska, 68131, United States
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Dayton Physician LLC-Miami Valley Hospital North
Dayton, Ohio, 45415, United States
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Dayton Physicians LLC-Atrium
Franklin, Ohio, 45005, United States
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Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, 45459, United States
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Dayton Physicians LLC-Upper Valley
Troy, Ohio, 45373, United States
-
Dayton Physicians LLC-Wayne
Greenville, Ohio, 45331, United States
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Delaware Clinical and Laboratory Physicians PA
Newark, Delaware, 19713, United States
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Delbert Day Cancer Institute at PCRMC
Rolla, Missouri, 65401, United States
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Flaget Memorial Hospital
Bardstown, Kentucky, 40004, United States
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Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington, 98405, United States
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Freeman Health System
Joplin, Missouri, 64804, United States
-
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, 45220, United States
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Good Samaritan Regional Health Center
Mount Vernon, Illinois, 62864, United States
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Greater Dayton Cancer Center
Kettering, Ohio, 45409, United States
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Greater Regional Medical Center
Creston, Iowa, 50801, United States
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Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington, 98310, United States
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Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington, 98370, United States
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Harrison Medical Center
Bremerton, Washington, 98310, United States
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Heartland Regional Medical Center
Saint Joseph, Missouri, 64506, United States
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Helen F Graham Cancer Center
Newark, Delaware, 19713, United States
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Highline Medical Center-Main Campus
Burien, Washington, 98166, United States
-
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
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Indu and Raj Soin Medical Center
Beavercreek, Ohio, 45431, United States
-
Iowa Lutheran Hospital
Des Moines, Iowa, 50316, United States
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Iowa Methodist Medical Center
Des Moines, Iowa, 50309, United States
-
Jewish Hospital
Louisville, Kentucky, 40202, United States
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Jewish Hospital Medical Center South
Shepherdsville, Kentucky, 40165, United States
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Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336, United States
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Katmai Oncology Group
Anchorage, Alaska, 99508, United States
-
Kettering Medical Center
Kettering, Ohio, 45429, United States
-
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
-
Littleton Adventist Hospital
Littleton, Colorado, 80122, United States
-
Longmont United Hospital
Longmont, Colorado, 80501, United States
-
Loyola Center for Health at Burr Ridge
Burr Ridge, Illinois, 60527, United States
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Loyola Medicine Homer Glen
Homer Glen, Illinois, 60491, United States
-
Loyola University Medical Center
Maywood, Illinois, 60153, United States
-
Marjorie Weinberg Cancer Center at Loyola-Gottlieb
Melrose Park, Illinois, 60160, United States
-
Marshfield Clinic - Ladysmith Center
Ladysmith, Wisconsin, 54848, United States
-
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, 54494, United States
-
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, 54729, United States
-
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, 54548, United States
-
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, 54401, United States
-
Marshfield Medical Center - Weston
Weston, Wisconsin, 54476, United States
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Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701, United States
-
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449, United States
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Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, 54868, United States
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Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, 54482, United States
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Mary Greeley Medical Center
Ames, Iowa, 50010, United States
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Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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McFarland Clinic PC - Ames
Ames, Iowa, 50010, United States
-
McFarland Clinic PC-Boone
Boone, Iowa, 50036, United States
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McFarland Clinic PC-Jefferson
Jefferson, Iowa, 50129, United States
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McFarland Clinic PC-Marshalltown
Marshalltown, Iowa, 50158, United States
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McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa, 50501, United States
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MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland, 21237, United States
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MedStar Georgetown University Hospital
Washington D.C., District of Columbia, 20007, United States
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Medical Oncology Hematology Consultants PA
Newark, Delaware, 19713, United States
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Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, 50309, United States
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Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, 50325, United States
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Mercy Cancer Center-West Lakes
Clive, Iowa, 50325, United States
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Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, 65401, United States
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Mercy Hospital Fort Smith
Fort Smith, Arkansas, 72903, United States
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Mercy Hospital Joplin
Joplin, Missouri, 64804, United States
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Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120, United States
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Mercy Hospital Saint Louis
St Louis, Missouri, 63141, United States
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Mercy Hospital South
St Louis, Missouri, 63128, United States
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Mercy Hospital Springfield
Springfield, Missouri, 65804, United States
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Mercy Hospital Washington
Washington, Missouri, 63090, United States
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Mercy Medical Center
Durango, Colorado, 81301, United States
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Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314, United States
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Mercy Medical Center-West Lakes
West Des Moines, Iowa, 50266, United States
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Methodist West Hospital
West Des Moines, Iowa, 50266-7700, United States
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Miami Valley Hospital
Dayton, Ohio, 45409, United States
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Miami Valley Hospital North
Dayton, Ohio, 45415, United States
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Miami Valley Hospital South
Centerville, Ohio, 45459, United States
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Midlands Community Hospital
Papillion, Nebraska, 68046, United States
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Mission Cancer and Blood - Laurel
Des Moines, Iowa, 50314, United States
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Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, 93420, United States
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Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, 93444, United States
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Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio, 45236, United States
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Orion Cancer Care
Findlay, Ohio, 45840, United States
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Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, 93401, United States
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Pacific Gynecology Specialists
Seattle, Washington, 98104, United States
-
Parker Adventist Hospital
Parker, Colorado, 80138, United States
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PeaceHealth Saint John Medical Center
Longview, Washington, 98632, United States
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PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225, United States
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PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664, United States
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PeaceHealth United General Medical Center
Sedro-Woolley, Washington, 98284, United States
-
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907, United States
-
Porter Adventist Hospital
Denver, Colorado, 80210, United States
-
Providence Alaska Medical Center
Anchorage, Alaska, 99508, United States
-
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, 97015, United States
-
Providence Newberg Medical Center
Newberg, Oregon, 97132, United States
-
Providence Portland Medical Center
Portland, Oregon, 97213, United States
-
Providence Regional Cancer Partnership
Everett, Washington, 98201, United States
-
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, 98520, United States
-
Providence Regional Cancer System-Centralia
Centralia, Washington, 98531, United States
-
Providence Regional Cancer System-Lacey
Lacey, Washington, 98503, United States
-
Providence Regional Cancer System-Shelton
Shelton, Washington, 98584, United States
-
Providence Regional Cancer System-Yelm
Yelm, Washington, 98597, United States
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Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, 91505, United States
-
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362, United States
-
Providence Saint Vincent Medical Center
Portland, Oregon, 97225, United States
-
Reid Health
Richmond, Indiana, 47374, United States
-
Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado, 80501, United States
-
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, 80907, United States
-
Rush - Copley Medical Center
Aurora, Illinois, 60504, United States
-
Rush-Copley Healthcare Center
Yorkville, Illinois, 60560, United States
-
Saint Anthony Hospital
Lakewood, Colorado, 80228, United States
-
Saint Anthony Regional Hospital
Carroll, Iowa, 51401, United States
-
Saint Anthony's Health
Alton, Illinois, 62002, United States
-
Saint Charles Health System
Bend, Oregon, 97701, United States
-
Saint Charles Health System-Redmond
Redmond, Oregon, 97756, United States
-
Saint Clare Hospital
Lakewood, Washington, 98499, United States
-
Saint Elizabeth Boardman Hospital
Boardman, Ohio, 44512, United States
-
Saint Elizabeth Hospital
Enumclaw, Washington, 98022, United States
-
Saint Elizabeth Regional Medical Center
Lincoln, Nebraska, 68510, United States
-
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio, 44501, United States
-
Saint Francis Cancer Center
Colorado Springs, Colorado, 80923, United States
-
Saint Francis Hospital
Federal Way, Washington, 98003, United States
-
Saint Joseph Hospital East
Lexington, Kentucky, 40509, United States
-
Saint Joseph London
London, Kentucky, 40741, United States
-
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky, 40504, United States
-
Saint Joseph Regional Cancer Center
Bryan, Texas, 77802, United States
-
Saint Joseph Warren Hospital
Warren, Ohio, 44484, United States
-
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri, 63011, United States
-
Saint Louis Cancer and Breast Institute-South City
St Louis, Missouri, 63109, United States
-
Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712, United States
-
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619, United States
-
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642, United States
-
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83686, United States
-
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, 83301, United States
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Saint Mary Corwin Medical Center
Pueblo, Colorado, 81004, United States
-
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802, United States
-
Saints Mary and Elizabeth Hospital
Louisville, Kentucky, 40215, United States
-
Southwest Oncology PC
Durango, Colorado, 81301, United States
-
Springfield Regional Cancer Center
Springfield, Ohio, 45504, United States
-
Springfield Regional Medical Center
Springfield, Ohio, 45505, United States
-
Swedish Cancer Institute-Edmonds
Edmonds, Washington, 98026, United States
-
Swedish Cancer Institute-Issaquah
Issaquah, Washington, 98029, United States
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Swedish Medical Center-Ballard Campus
Seattle, Washington, 98107, United States
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Swedish Medical Center-Cherry Hill
Seattle, Washington, 98122-5711, United States
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Swedish Medical Center-First Hill
Seattle, Washington, 98122, United States
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The Carle Foundation Hospital
Urbana, Illinois, 61801, United States
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TidalHealth Nanticoke / Allen Cancer Center
Seaford, Delaware, 19973, United States
-
TriHealth Cancer Institute-Anderson
Cincinnati, Ohio, 45255, United States
-
TriHealth Cancer Institute-Westside
Cincinnati, Ohio, 45247, United States
-
Trinity Regional Medical Center
Fort Dodge, Iowa, 50501, United States
-
UM Sylvester Comprehensive Cancer Center at Aventura
Aventura, Florida, 33180, United States
-
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, 33146, United States
-
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, 33442, United States
-
UM Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, 33176, United States
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UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, 33324, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136, United States
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University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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UofL Health Medical Center Northeast
Louisville, Kentucky, 40245, United States
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Upper Valley Medical Center
Troy, Ohio, 45373, United States
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Wayne Hospital
Greenville, Ohio, 45331, United States
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