LOCALLY ADVANCED MELANOMA
Clinical trials for LOCALLY ADVANCED MELANOMA explained in plain language.
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Could less medicine be enough? study tests lower cancer drug doses
Disease control Recruiting nowThis study is testing a new approach to dosing a cancer immunotherapy drug called atezolizumab. Researchers want to see if they can use blood tests to personalize the timing and amount of the drug, aiming to use lower doses less often while still keeping it effective. The goal is…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Custom cancer vaccine designed to train your own immune system
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to teach the body's immune system to recognize and attack a patient's specific cancer. It is being given alongside an existing immunotherapy drug (pembrolizumab) to adults with advanced solid tumors that have spread. The …
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Targeted pill trial aims to control advanced cancers by blocking key growth signals
Disease control Recruiting nowThis study is testing an oral medication called avapritinib for people with advanced solid tumors that have spread and have specific genetic changes (mutations in the CKIT or PDGFRA genes). The drug aims to block the signals that help these tumor cells grow, potentially controlli…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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Can a special drink make cancer treatment safer?
Symptom relief Recruiting nowThis study is testing whether a nutritional supplement called Impact® can help reduce severe side effects in people with advanced melanoma who are receiving immunotherapy drugs. Twenty patients will take the supplement drink before and during their standard cancer treatment. Rese…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: NA • Sponsor: Fondazione Melanoma Onlus • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Scientists probe immune secrets of new melanoma drug combos
Knowledge-focused Recruiting nowThis study aims to understand how the immune system responds to two different two-drug immunotherapy combinations in patients with advanced melanoma that cannot be surgically removed. Researchers will analyze blood and tumor samples from 20 participants to see how specific immune…
Matched conditions: LOCALLY ADVANCED MELANOMA
Sponsor: John Kirkwood • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists seek clues in blood to unlock cancer treatment mystery
Knowledge-focused Recruiting nowThis study aims to understand why some patients with advanced cancers like melanoma and lung cancer respond well to a common immunotherapy (anti-PD-1), while others do not. Researchers will collect blood samples from 500 patients to measure specific markers in immune cells during…
Matched conditions: LOCALLY ADVANCED MELANOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC