LOCALLY ADVANCED MELANOMA
Clinical trials for LOCALLY ADVANCED MELANOMA explained in plain language.
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Cancer trial tests 'Less is More' approach to powerful drug
Disease control Recruiting nowThis study is testing a new method for giving the cancer drug atezolizumab. Researchers want to see if they can use lower doses, given less often, by carefully monitoring drug levels in a patient's blood. The goal is to see if this personalized approach can still control the canc…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Targeted pill trial aims to control advanced cancers by blocking key growth signals
Disease control Recruiting nowThis study is testing an oral medication called avapritinib for people with advanced solid tumors that have spread and have specific genetic changes (mutations in the CKIT or PDGFRA genes). The drug aims to block the signals that help these tumor cells grow, potentially controlli…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Nutritional boost may shield cancer patients from harsh treatment side effects
Symptom relief Recruiting nowThis study is testing whether a special nutritional drink called Impact® can help reduce severe side effects in people with advanced melanoma who are receiving immunotherapy drugs. Twenty patients will drink Impact® before and during their standard immunotherapy treatment. Resear…
Matched conditions: LOCALLY ADVANCED MELANOMA
Phase: NA • Sponsor: Fondazione Melanoma Onlus • Aim: Symptom relief
Last updated Mar 18, 2026 14:40 UTC
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Scientists probe immune secrets of new melanoma drug combos
Knowledge-focused Recruiting nowThis study aims to understand how the immune system responds to two different two-drug immunotherapy combinations in patients with advanced melanoma that cannot be surgically removed. Researchers will analyze blood and tumor samples from 20 participants to see how specific immune…
Matched conditions: LOCALLY ADVANCED MELANOMA
Sponsor: John Kirkwood • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists seek clues in blood to unlock cancer treatment mystery
Knowledge-focused Recruiting nowThis study aims to understand why some patients with advanced cancers like melanoma and lung cancer respond well to a common immunotherapy (anti-PD-1), while others do not. Researchers will collect blood samples from 500 patients to measure specific markers in immune cells during…
Matched conditions: LOCALLY ADVANCED MELANOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC