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Sleep or awake? study tests best anesthesia for stroke treatment

NCT ID NCT03229148

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 332 stroke patients to see if general anesthesia or conscious sedation is better during a procedure to remove blood clots from the brain. The goal was to find which method leads to better recovery and fewer complications within the first week. The results could help doctors make safer choices for future stroke care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could help doctors choose the best anesthesia method for stroke patients undergoing clot removal, potentially improving recovery and reducing complications.
What could go wrong
This trial is completed but results may not apply to all stroke types or hospitals. The comparison is between two standard procedures, so no breakthrough cure is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

332 people

The number who actually took part.

Started

Aug 2017

Finished

Jun 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Acute anterior circulation ischemic stroke (terminal portion of the internal carotid artery, middle cerebral artery), with indication for radiological mechanical thrombectomy assessed by the neurology / neuroradiology team * Over 18 years of age * Benefiting from an affiliation to the French Social Security system * Patient or familly informed consent. In case of patient incapacity and no family present, and due to the emergency of the procedure, the patient may be included on the sole decision of the investigator (emergency procedure with subsequent differed consent). Exclusion Criteria: * Altered vigilance defined by score ≥ 2 at item 1a "level of consciousness" of the NIHSS score * Altered previous autonomy, defined by a modified Rankin score (mRS)\> 1 * Acute ischemic stroke of posterior circulation or anterior cerebral artery * Associated brain haemorrhage * Pregnant or nursing women * Patient under law protection * Stroke complicating another acute illness or postoperative stroke.

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Conditions

The condition(s) this trial relates to.

middle cerebral artery infarction stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Conscious sedation Stroke Thrombectomy

Contacts and locations

Locations

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, Auvergne, 63003, France

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