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AI trained to spot hidden tooth infections on routine x-rays

NCT ID NCT05888935

Diagnosis Sponsor: Centre Hospitalier Régional Metz-Thionville Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether an artificial intelligence program can detect periapical lesions (infections at the tip of a tooth root) on common panoramic dental X-rays. The AI is trained using 3D cone-beam CT scans as the gold standard. Researchers will enroll 2000 patients who have had both types of imaging within three months. If the AI works well, it could help dentists catch these infections earlier without needing more advanced scans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Artificial intelligence algorithm
What this could lead to
If successful, this AI could help dentists find hidden tooth infections earlier using a common, low-radiation X-ray, potentially reducing the need for more advanced scans.
What could go wrong
This is an early-stage algorithm test, not a treatment. The AI may not be accurate enough in real-world use, and the study only includes patients who already had both types of scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with periapical lesions

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who have had CBCT and panoramic dental imaging with less than 3 months between the two examinations Exclusion Criteria: * Patients who refused to participe in the study.

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Conditions

The condition(s) this trial relates to.

Periapical Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periapical diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHR Metz-Thionville/Hopital de Mercy

    RECRUITING

    Metz, 57085, France

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